降纤酶对脑梗塞急性期患者血液流变学的影响  

The influence of defibrase on hemorheology of patients with cerebral infarct in acute stage

作　　者：于永发[1] 张玉梅[1] 张丽梅[1] 潘维芝 吴江[1] 

机构地区：[1]哈尔滨医科大学附属第二医院神经科,黑龙江哈尔滨150086

出　　处：《哈尔滨医科大学学报》2001年第1期27-28,共2页Journal of Harbin Medical University

摘　　要：目的　探讨降纤酶对脑梗塞急性期患者血液流变学的影响 ,为降纤酶的临床应用提供依据。方法　脑梗塞发病后 2 4h内的患者 40例 ,检测应用降纤酶治疗前及治疗后 3、7、14天的血液流变学指标的变化。结果　治疗后纤维蛋白原、全血粘度、血浆粘度、红细胞聚集指数、红细胞压积均不同程度下降。结论　降纤酶可降低纤维蛋白原、抑制红细胞聚集、降低血液粘度 ,从而改善微循环。Objective To observe the influence of defibrase on hemorheology of patients with infarct in acute stage.It may provide evidence to the clinical using of defibrase.Methods At the onset <24h cases were treated with defibrase.Detected the hemorheology before therapy and 3,7,14 day after therapy.Results There were decreased level of fibrinogen,viscosity of whole blood and plasma,accumulating index of red blood cell,hematocrit.Conclusion Defibris could decrease fibrinogen,inhibit red blood cell accumulating,decrease viscosity of whole blood,as a result improved microcirculation.

关 键 词：降纤酶 脑梗塞 血液流变学 急性期 药物治疗 

分 类 号：R743.330.5[医药卫生—神经病学与精神病学] R973.2[医药卫生—临床医学]