浙江省20002009年肿瘤登记地区脑肿瘤发病与死亡分析  

Incidence and mortality of brain tumor in areas with cancer registration of Zhejiang province,from 2000 to 2009

作　　者：李辉章[1] 毛伟敏[1] 汪祥辉[1] 余传定[1] 杜灵彬[1] 

机构地区：[1]浙江省肿瘤医院浙江省肿瘤防治办公室,杭州310022

出　　处：《中华流行病学杂志》2014年第3期285-288,共4页Chinese Journal of Epidemiology

摘　　要：目的分析浙江省肿瘤登记地区2000-2009年脑肘：瘤的发病与死亡情况。方法数据来源于浙江省6个肿瘤登记处上报于浙江省肿瘤防治办公室的肿瘤发病、死亡及人口资料，分别计算发病（死亡）例数、粗发病率（死亡率）、构成比和顺位、中国标准人口构成（中标率）、Segi’s世界标准人口构成（世标率）、累积率、截缩率、年龄别发病率（死亡率）、发病率（死亡率）年度变化百分比（APC）及95％CI等指标。结果2000-2009年浙江省6个肿瘤登记地区共计报告脑肿瘤新发病例5123例，占癌症新发病例的3．14％。脑肿瘤发病率为8．53／10万，中标率为5．72／10万，世标率为6．64／10万，居癌症发病顺位的第7位。脑肿瘤年龄别发病率随年龄增长而增加，在70～74岁组达高峰（24．09／10万）。脑肿瘤发病率历年变化呈总体增长趋势，发病率从2000年的6．87／10万上升到2009年的8．35／10万，APC为1．58％（95％C1：-2．17％-5．47％），差异无统计学意义。共计报告脑肿瘤死亡病例2357例，占癌症死亡病例的2．47％。脑肿瘤死亡率为3．92／10万，中标率为2．45／10万，世标率为2．96／10万，居癌症死因顺位的第7位。脑肿瘤年龄别死亡率在0～39岁期间处于较低水平，在80-84岁组达高峰（17．64／10万）。脑肿瘤死亡率历年变化呈现波动下降趋势，死亡率从2000年的4．30／10万上升到2006年4．63／10万的最高水平，然后降至2009年的3．83／10万，APC为-0．65％（95％CI：-3．35％～2．12％），差异无统计学意义。结论浙江省肿瘤登记地区脑肿瘤发病呈上升趋势，发病率和死亡率处于较高水平。中老年人群特别是70岁以上老年人群是脑肿瘤发病和死亡的重点人群。Objective To investigate the incidence and mortality of brain tumor in Zhejiang cancer registration areas from 2000 to 2009. Methods Data from 6 Cancer registration areas of Zhejiang province were collected. Number of cases, crude rates, proportions, age standardized rates, cumulate rates, cut rates, age-specific rates and annual percentage change （APC, 95% CI） of brain tumor incidence and mortality were analyzed. Results There were 5 123 new diagnosed brain tumor cases in Zhejiang cancer registration areas, accounting for 3.14% of all the new cancer cases. The incidence rate of brain tumor was 8.53/100 000, and the standard：ized incidence rate by Chinese population was 5.72/100 000, ranking the 7th in cancer incidence spectrum of anatomic sites. Age- specific incidence of brain tumor increased along with age, and peaked among 70-74 age groups （24.09/100 000）. The annual incidence rate of brain tumor increased from 2000 （6.87/100 000） to 2009（8.35/100 000）, with APC as 1.58%（95%CI：-2.17%-5.47%, no statistical significance）. A total of 2 357 deaths caused by brain tumor were reported from 2000-2009, accounting for 2.47% of all the cancer death cases. Mortality rate on brain tumor appeared to be 3.92/100 000, with the standardized mortality rate by Chinese population as 2.45/100 000, ranking the 7th in cancer mortality spectrum of anatomic sites. The age-specific mortality of brain tutaor remained low among 0-39 year-olds, and reached the peak at 80-84 age groups （17.64/100 000）. The annual mortality rate of brain tumor decreased from 2000 （4.30/100 000） to 2009 （3.83/100 000） with minor fluctuation, andthe APC was -0.65% （95%C/： -3.35%-2.12%, no statistical significance）. Conclusion Brain tumors incidence and mortality in Zhejiang cancer registration areas were at a relatively high level. People who were at middle-age, especially above 70 years old should be the key targets for protection on this disease. Brain tumor incidence rates increased annually in Zhejiang, which sh

关 键 词：脑肿瘤 发病 死亡 

分 类 号：R739.41[医药卫生—肿瘤]