急性淋巴细胞白血病24例形态学与免疫学分型分析  

Analysis of morphology and immunophenotyping of acute lymphoblastic leukemia: 24 cases

作　　者：程松[1] 郭婧澜[1] 魏兰[1] 赵华[1] 

机构地区：[1]泸州医学院附属医院检验科,四川省泸州市646000

出　　处：《临床合理用药杂志》2014年第5期19-20,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨急性淋巴细胞白血病(ALL)形态学与免疫学分型的关系,以提高白血病的诊断水平。方法针对24例ALL患者行骨髓细胞形态学、骨髓细胞化学染色及免疫分型检测,比较2者在ALL分型上的异同。结果24例ALL患者中,FAB分型L1 15例、L2 7例、L3 2例;WHO免疫分型T-ALL 7例、B-ALL 17例。结论免疫学分型是诊断ALL的重要手段,是对形态学分型的补充和修正,它对ALL患者的诊断、治疗和判断预后具有重要的指导意义。Objective To explore the relationship between morphology and immunophenotyping of acute lymphoblas- tic leukemia （ALL） and improve the diagnosis level of leukemia. Methods Choosing 24 cases of patients with ALL in our hospital, and then taking their bone marrow for morphology, cytochemistry and immunophenotype detection. The similarities and differences of 2 groups was compared in the ALL type. Results There are L1 15 cases, L2 7 cases and 1.3 2 eases according to FAB classification. There are T-ALL 7 cases and B-ALL 17 cases according to WHO immunological classification. Conclusion Immunological classification is a significant mean to the diagnosis of ALL,which is the supplement and correction to morpho- logical classification and has important directive significance for diagnosis, treatment and prognosis of ALL.

关 键 词：急性淋巴细胞白血病 FAB分型 免疫学分型 

分 类 号：R733.71[医药卫生—肿瘤]