1171例舌癌的治疗与预后分析  

Clinical analysis of treatment and prognosis on 1171 cases of tongue carcinoma

作　　者：何升腾[1] 焦晓辉[1] 刘欧胜[2] 唐瞻贵[2] 

机构地区：[1]哈尔滨医科大学附属口腔医院口腔颌面外科,哈尔滨150001 [2]中南大学口腔医学院口腔颌面外科,长沙410008

出　　处：《重庆医学》2014年第6期671-673,共3页Chongqing medicine

摘　　要：目的：探讨和分析舌癌的治疗方法及其预后的影响因素。方法对2001～2007年在中南大学口腔医学院和哈尔滨医科大学附属口腔医学院住院的1171例舌癌患者进行回顾性研究，对其年龄、性别、癌变部位、临床分期、病理分级、治疗方法等进行分析，探讨影响舌癌预后的因素。结果舌体癌患者生存率明显高于舌根癌；临床分期高、细胞分化程度低者其术后生存率较低；手术切缘阳性者、淋巴结转移者、骨受侵犯者其预后差；下颌骨的切除与否与预后无相关性（P＞0．05），术后即刻行皮瓣修复与否对生存率影响差异无统计学意义（P＞0．05）。结论切缘状况与临床分期是影响舌癌预后的独立因素，早期发现，早期诊断及治疗对提高舌癌患者的生存率有显著意义。Objective To investigate treatment and related prognostic factors of tongue carcinoma .Methods Clinical and patho-logical parameters of 1 171 cases of tongue carcinoma treated in Department of Oral and Maxillofacial Surgery ,School of Stomatolo-gy ,Harbin Medical University and Central South University from 2001 to 2007 were retrospective analyzed ,which included age , gender ,location ,pathological grade ,clinical TNM stages ,and treatment modality .Results After 3 to 5 year of follow-up ,survival rate of patients with tongue body carcinoma was obviously higher than that on the base of tongue .High clinical stage ,low cell dif-ferentiation degree of the postoperative patients had lower survival rate .The prognosis of patients with positive surgical margins and positive lymph node metastasis was poorer .The survival rate had no correlation with excision of mandible .When the tongue was re-stored with flaps ,the safety margins were increased to reduce recurrence .Conclusion Clinical TNM stages and surgical margin are independent prognostic factors for tongue cancer .Early diagnosis and treatment are vital to increase the survival rate of patients .

关 键 词：舌肿瘤 治疗 预后 生存率 

分 类 号：R739.8[医药卫生—肿瘤]