弹性应变率比值法对甲状腺癌的诊断价值  

The value of strain ratio method in diagnosis of benign and malignant thyroid nodules by ultrasonic elastography

作　　者：张伟[1] 朱亚[1] 吴海燕[1] 张慧琴[1] 尹慧[1] 向双[1] 

机构地区：[1]湖北医药学院附属东风医院,湖北十堰442008

出　　处：《中国中西医结合影像学杂志》2014年第1期37-38,41,F0003,共4页Chinese Imaging Journal of Integrated Traditional and Western Medicine

摘　　要：目的：探讨弹性应变率比值法对甲状腺癌的诊断价值.方法：对190例患者的211个甲状腺结节分别行常规超声和弹性超声检查,测量结节周围正常甲状腺组织与结节间的弹性应变率比值（E2/E1）,并将结果与术后病理结果进行比较.结果：弹性应变率比值法诊断甲状腺癌的ROC曲线下面积（AUC）为0.902（95%CI,0.862~0.942）;良性结节的E2/E1均值为0.59±0.17,甲状腺癌的E2/E1均值为0.31±0.10,两者间比较差异有统计学意义（P＜0.05）.超声弹性应变率比值法与常规超声对甲状腺癌的检出率比较差异无统计学意义（P＞0.05）,但联合应用两法较单独应用弹性应变率法敏感性显著提高（P＜0.05）.结论：超声弹性应变率比值法作为一项相对客观的诊断甲状腺良恶性结节的半定量指标,具有较高的诊断准确性,与常规超声联合应用可提高甲状腺癌的检出率.Objective： To evaluate the accuracy of the strain ratio method in diagnosis of benign and malignant thyroid nodules by ultrasonic elastography. Methods： 211 nodules in 190 cases were scanned with high frequency sonography and elastography, measuring the strain ratio （E2/E1） of normal thyroid tissue and mass organizational, the results were compared with pathologi- cal diagnosis accordingly. We established the Receiver operating characteristic （ROC） curve to analyze the accuracy of the strain ratio method in diagnosis of benign and malignant nodules and then determined the cut-off point for the strain ratio. Re- sults： The area under the ROC curve （AUC） of strain ratio method in diagnosis of benign and malignant nodules was 0. 902 （95CI, 0. 862±0. 942）. The strain ratio of benign tumors （0.59±0.17）was significantly higher than that of malignant ones （0.31±0.10）,（P〈0.05）. The difference between strain ratio method and conventional ultrasound was no significant（P〈 0.05 ）, but the combined application of the two methods significantly improved the positive detection rate than one method （P〈0.05）. Conelusions~ The strain ratio method has a high accuracy in diagnosis of benign and malignant thyroid nodules,and it is worth of application in clinic.

关 键 词：超声检查 甲状腺肿瘤 诊断 

分 类 号：R736.1[医药卫生—肿瘤]