电针腧穴联合当飞利肝宁治疗非酒精性脂肪性肝炎的临床研究  

Clinical Research on the Electro-acupuncture Combined with DangfeiLiganning Capsule in the Treatment of Nonalcoholic Fatty Liver Disease

作　　者：张林[1] 江艳燕[1] 邓晓玲[1] 顾雪梅[1] 桂程丽[1] 

机构地区：[1]湖北医药学院附属人民医院,湖北十堰442000

出　　处：《现代生物医学进展》2014年第5期905-907,901,共4页Progress in Modern Biomedicine

摘　　要：目的:探讨电针腧穴联合当飞利肝宁治疗非酒精性脂肪性肝炎(nonalcohlic steatohepatitis,NASH)的临床疗效及其安全性。方法:选择符合2010年非酒精性脂肪性肝病诊疗指南[1]诊断标准的80例非酒精性脂肪性肝炎患者,随机分为联合组(电针联合当飞利肝宁治疗组)和对照组(护肝宁治疗组)各40例,两组患者均在纠正不良生活方式、控制饮食(BMI<24)、适量有氧运动等的基础上给予相应的治疗,对照组仅服用护肝宁,3次/d,联合组服用当飞利肝宁及电针腧穴治疗。观察和比较两组的疗效、血清转氨酶、血脂水平、脂肪肝程度变化和不良反应的发生情况。结果:联合组和对照组的治疗总有效率分别为90.0%和62.5%,两组总有效率比较有显著性差异(P<0.05)。治疗后,联合组患者的血清转氨酶、血脂水平均较对照组显著降低(P<0.05)。治疗中两组均未发现明显不良反应。结论:电针腧穴联合当飞利肝宁对非酒精性脂肪性肝炎有较好的治疗效果,具有很高的临床应用价值。Objective： To investigate the efficacy and safety of electro-acupuncture combined with Dangfei Liganning Capsule in the treatment of Nonalcoholic Fatty Liver Disease （NASH）. Methods： Eighty patients who were diagnosed as NASH according to 2010 nonalcoholic fatty liver disease diagnosis and treatment guideline were randomly divided into the combination group （electro-acupunctu- re combined with Dangfei Liganning Capsule） and control group （Hugan Ning）. The patients in both groups were treated by correcting unhealthy lifestyles, dietary control （BMI〈24）, moderate aerobic exercise on the basis of the corresponding treatment. The control group was given Hugan Ning, 3 times/d, while the combination group was given Dangfei Liganning Capsule with electro-acupuncture acupoin- ts. The changes ofALT, GGT levels, the severity of fatty liver and the adverse reaction were observed and compared. Results： The total effective rate of combination group and control group were respectively 90.0% and 62.5% （P〈0.05）. The aminotransferase and blood fat of combination group were decreased significantly than those of the control group （P〈0.05）. No significant adverse reaction was found. Conclusion： Electro-acupuncture combined with Dangfei Liganning Capsule may obtain a favorable effect on nonalcoholic fatty liver disease and was of great clinical value.

关 键 词：非酒精性脂肪性肝炎 电针 当飞利肝宁 临床疗效 

分 类 号：R575.5[医药卫生—消化系统]