食管癌贲门癌胃癌高危人群的内镜筛查结果分析  

Analysis of results of endoscopic screening of esophageal, gastric cardia and gastric cancers in high risk population

作　　者：张建功[1] 王福让[1] 张亚冰[2] 全培良[1] 刘曙正[1] 孙喜斌[1] 陆建邦[1] 

机构地区：[1]郑州大学附属肿瘤医院河南省肿瘤医院肿瘤防治办公室,450008 [2]郑州大学河南省医药科学研究院

出　　处：《中华肿瘤杂志》2014年第2期158-160,共3页Chinese Journal of Oncology

摘　　要：目的探讨筛查人群年龄、性别和活检率等对于食管癌胃癌检出率和早诊率的影响。方法选择河南省食管癌9个高发市县，将40～69岁设定为高危人群。排除有胃镜检查禁忌证者，按照国家癌症早诊早治技术方案，对筛查对象的食管、贲门、胃进行内镜检查并做组织学诊断。结果3年共筛查40156人，发现各类癌前病变18459例，占筛查人群的46．0％；癌症916例，检出率为2．3％，其中早期癌763例，早诊率为83．3％。结论在食管癌、胃癌高发区的高危人群中开展内镜筛查对实施上消化道癌早诊早治是可行的。对于影响筛查效果的相关因素进行探索分析，有助于食管癌、贲门癌和胃癌早诊早治项目的深入开展。Objective To summarize the results of endoscopic screening of esophageal, gastric cardiac and gastric cancers in the high-risk population, and analyze the influencing factors such as age, gender and biopsy rate on their detection and early diagnosis rates. Methods Nine high incidence cities and counties of esophageal cancer in Henan province were included in this study. People aged 40-69 years were set to the target population. Excluding contraindications for gastroscopy, in accordance with the national technical scheme of early cancer diagnosis and treatment, gastroscopic screening and biopsy pathology for human esophageal, cardiac and gastric cancers were carried out. Results During the 3-year period, a total of d0 156 subjects were screened. Among them, 18 459 cases of various precancerous lesions （46.0%） were detected. The cancer detection rate was 2.3% （916 cases）, including 763 cases of early cancers. The diagnosis rate of early cancers was 83.3%. Precancerous lesions were detected in 9297 cases （25.2%） for esophagus and 9162 cases （22.8%） for gastric cardia as well as stomach, respectively. Conclusions The results of this study demonstrate that endoscopic screening is feasible for early detection, diagnosis and treatment of esophageal, gastric cardia and gastric cancers among high risk population in high incidence area. Exploration analysis of relevant affecting factors may help to further improve the screening project for early diagnosis and treatment of those cancers.

关 键 词：食管肿瘤 胃肿瘤 人口特征 普查 

分 类 号：R735[医药卫生—肿瘤]