三种仪器测量LASEK术后中央角膜厚度的比较  

Comparison of central corneal thickness measurements after LASEK by three instruments

作　　者：彭晓娟[1,2] 田烨[1,2] 刘四英[1,2] 陈季生[1,2] 

机构地区：[1]湘西自治州人民医院眼科 [2]吉首大学第一附属医院眼科,中国湖南省吉首市416000

出　　处：《国际眼科杂志》2014年第3期477-479,共3页International Eye Science

摘　　要：目的:比较光学相干断层扫描(optical coherence tomography,OCT)、角膜内皮计与超声测厚仪测量准分子激光上皮下角膜磨镶术(laser subepithelial keratomileusis,LASEK)术后患者中央角膜厚度(CCT)的差异性和相关性。方法:选取LASEK术后6mo复诊的近视患者49例96眼,对每位患者分别用OCT、角膜内皮计、超声测厚仪三种仪器测量其CCT,数据统计分析采用配对t检验和Pearson相关性分析。结果:OCT、角膜内皮计、超声测厚仪测量CCT的平均值为分别为475.15±33.67,447.80±34.11,465.18±34.23μm。手术预留CCT平均值为431.22±35.32μm。三种仪器所测量结果之间两两比较差异均有统计学意义(P<0.05)。线性相关显示超声测厚仪与OCT、角膜内皮计两种仪器之间存在正相关(r=0.949,0.983,P<0.01)。LASEK术后实际CCT较手术预留角膜厚度要厚。结论:三种仪器的中央角膜厚度测量值不可互换。AIM： To compare the differences and the relationships of central corneal thickness （ CCT） measurements among optical coherence tomography （ OCT ） , Tomey pachymetry and ultrasound pachymetry after laser assisted subepithelial keratomileusis （ LASEK） . METHODS：Forty-nine patients （ 96 eyes ） with myopia after 6mo of LASEK were assigned to measure the CCT by OCT, Tomey pachymetry and ultrasound pachymetry. Paired t-test and Pearson correlation analysis was used for statistical analysis. RESULTS： The mean CCT measured by OCT, Tomey pachymetry and ultrasound pachymetry was （ 475.15 ± 33.67μm）, （447.80 ±34.11μm）, （465.18 ±34.23μm）, respectively.Surgery reserved mean CCT was （ 431.22 ± 35.32 ）μm.There were statistically differences between two comparative measured results （P＆lt;0.05）.Ultrasound pachymetry had a positive correlation with OCT and Tomey pachymetry （ P ＆lt;0.01 ）, and the correlation coefficient was 0.949 and 0.983, respectively.The actual CCT of 6mo post-operation was thicker than surgery reserved CCT. CONCLUSION： The CCT measurements of three instruments were not interchangeable.

关 键 词：光学相干断层扫描 角膜内皮计 超声角膜测厚仪 中央角膜厚度 

分 类 号：R779.63[医药卫生—眼科]