肝硬化患者血清总胆汁酸水平与child分级的关系  

The relationship of serum total bile-acids level and child-grade in patients with cirrhosis

作　　者：邱隆敏[1] 李佳[1] 何应中[1] 杨福秀[1] 

机构地区：[1]遵义医学院附属医院传染科,563003

出　　处：《贵州医药》2001年第2期111-112,共2页Guizhou Medical Journal

摘　　要：目的探讨肝硬化患者血清总胆汁酸水平与child分级的关系。方法血清总胆汁酸利用酶法测定 ,仪器选用HITACHI7170A自动分析仪。结果与健康对照组比较 ,各级child分级肝硬化患者血清总胆汁酸水平明显升高 (P <0 0 0 1) ;且随着childA、B、C级的升高而递增 ,各级间比较差异有极显著意义 (P <0 0 0 1) ;相关分析显示肝硬化患者血清总胆汁酸水平与child pugh积分呈正相关 (γ=0 72 ,P <0 0 1)。结论总胆汁酸是反映肝实质损害的一项灵敏指标 ,可以较好的反映肝硬化病情的严重程度。Objective To study the relationship of serum total bile acids level and child grade in patients with cirrhosis. Methods The serum total bile acids were detected by enzyme method. Results The compared with the control group (healthy persons) that the serum total bile acids level of each child grade in patients with cirrhosis were significantly high ( P <0.001). Higher and higher with the promotion of child A, B, C class, there was a significant difference among each class ( P <0.001). The relevant analysis showed that the serum total bile acids level and child pugh total marks was positive correlation (r=0.72, P <0.01). Conclusion The total bile acids was a sensitive index to reflect the damage of the liver and to reflect the serious degree of the disease.

关 键 词：肝硬化 总胆汁酸 CHILD分级 测定 

分 类 号：R575.2[医药卫生—消化系统]