动态动脉硬化指数与颅内、外动脉狭窄的相关性研究  

Correlation between ambulatory aterial stiffness index and extracranial and intracranial arterial stenosis

作　　者：芦军[1] 赵伟丽[1] 孙晓红[1] 崔其福[1] 

机构地区：[1]赤峰学院附属医院,024000

出　　处：《实用医学杂志》2014年第5期754-757,共4页The Journal of Practical Medicine

基　　金：内蒙古自治区自然科学基金项目(编号:2009MS1138)

摘　　要：目的:观察146例缺血性脑血管病患者动态动脉硬化指数(ambulatory arterial stiffness index,AASI)在颅内、外动脉狭窄中的变化,评价AASI与颅内、外动脉狭窄程度及数量的相关性,以指导临床预防。方法:对入组患者行头颈部CT血管成像(CTA)评价颅内、外动脉狭窄程度。以狭窄血管支数的不同分为无狭窄组、1支动脉狭窄组、2支动脉狭窄组、3支及以上动脉狭窄组。监测动态血压计算AASI。结果:(1)颅外动脉狭窄程度各组AASI值未见统计学差异(P=0.614)。(2)AASI与颅内动脉狭窄程度呈正相关(r=0.743,P<0.05)。(3)AASI和3支及以上病变组呈正相关(r=0.797,P<0.05)。结论:AASI颅内动脉狭窄程度及病变支数呈正相关,与颅外动脉狭窄程度无明显相关。Objective To evaluate the relationship between ambulatory arterial stiffness index （AASI） and intracranial and extracranial arterial stenosis in 146 patients with ischemie cerebrovascular disease. Methods Degree of intracranial and extracranial arterial stenosis in 146 patients with iscbemic cerebrovascular disease was assessed by CT angiography （CTA）. Then all patients were divided into 4 groups according to the numbers of branches with stenosis： no stenosis group, 1 branch group, 2 branches group, and 3 and more than 3 branches group. Dynamic blood pressure was monitored to calculate the AASI. Results There was no significant difference of AASI among the extraeranial arterial stenosis groups （P = 0.614）. AASI was positively correlated with the degree of intracranial artery stenosis （r = 0.743, P 〈 0.05）, and with 3 and more intracranial artery branches stenosis （r = 0.797, P 〈 0.05）. Conclusion AASI is closely correlated with the degree and numbers of branches of intracranial artery stenosis.

关 键 词：脑缺血 动态动脉硬化指数 颅内动脉狭窄 颅外动脉狭窄 

分 类 号：R743.3[医药卫生—神经病学与精神病学]