胃炎与幽门螺杆菌感染326例相关性分析  

Correlation between 326 gastritis cases and Helicobacter pylori infection

作　　者：赵丽华[1] 林竞[1] 位嘉[1] 林秋兰[1] 王克杰[1] 吴倩[1] 闫红燕[1] 

机构地区：[1]民航总医院病理科,北京100123

出　　处：《诊断病理学杂志》2014年第2期84-86,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨胃炎的严重程度、活动性、肠化生、萎缩性、腺体不典型增生与幽门螺杆菌(Hp)感染的关系;为临床胃炎抗Hp治疗提供理论依据。方法对胃镜诊断为胃炎的326例患者行活检病理诊断,按慢性炎症、萎缩、肠上皮化生、异型性、活动性分报告,进行免疫组化Hp检测及两者相关性分析。结果 Hp感染的细菌密度与慢性胃炎的严重程度、活动性、萎缩程度及腺体不典型增生均呈显著正相关(P<0.01),但与肠化严重程度不相关(P>0.01)。结论 Hp感染的细菌密度与慢性胃炎严重程度、活动性、萎缩程度、腺体不典型增生呈显著正相关,与肠上皮化生程度无相关性。Objetive To investigate relationship between infection of Helicobacter pylori （Hp） and gastritis degree,activity of gastritis,intestinal metaplasia,atrophy and dysplasia,and to make profit for clinicians to select appropriate antiHp therapy.Methods After gastroendoscopy,326 cases of gastritis were taken biopsy.Histological diagnoses were classified as chronic inflammation,active gastritis,atrophy,intestinal metaplasia and dysplasia.Correlation between density of Helicobacter pylori and chronic gastritis were analyzed.Results ① There was statistic relationship between density of Helicobacter pylori and degree of gastritis.② There was statistic relationship between density of Helicobacter pylori and degree of activity of gastritis.③ There was statistic relationship with density of Helicobacter pylori and gastric atrophy.④ There was statistic relationship with density of Helicobacter pylori and dysplasia.⑤ There was no statistic relationship between density of Helicobacter pylori and intestinal metaplasia.Conclusion The density of Helicobacter pylori is related to severity of the gastritis,activity of gastritis,gastric atrophy and dysplasia.There is no relationship between density of Helicobacter pylori and intestinal metaplasia.

关 键 词：慢性胃炎 幽门螺杆菌 相关分析 

分 类 号：R573.3[医药卫生—消化系统]