分水岭脑梗死早期复发及相关因素分析  

Analysis of related factors of early recurrence to cerebral watershed infarction

作　　者：王万华[1] 马召玺[1] 张炎[1] 王红洲[1] 曹勇军[2] 赵合庆[2] 

机构地区：[1]昆山市第一人民医院神经内科,215300 [2]苏州大学附属第二医院神经内科

出　　处：《临床神经病学杂志》2014年第1期26-29,共4页Journal of Clinical Neurology

摘　　要：目的 探讨分水岭脑梗死（CWI）早期复发的相关因素.方法 收集121例急性CWI患者的临床资料,并随访1个月.根据复发情况,分为未复发组及复发组,分析CWI早期复发的相关因素.结果 根据复发情况分为复发组36例,无复发组85例.与无复发组比较,复发组血管狭窄程度≥90％、扩容治疗的比率及收缩压显著降低,不稳定斑块及积极降压的比率显著升高（P ＜0.05 ～0.01）.多因素Logistic回归显示,不稳定斑块（OR=4.929,95％CI：1.491 ～ 16.296,P＜0.01）、狭窄程度≥90％（OR=6.072,95％CI：2.115 ～17.430,P＜0.01）及积极降压（OR=3.840,95％CI：1.418～10.400,P＜0.01）是CWI早期复发的独立危险因素.结论 不稳定斑块、脑血管重度狭窄、降压治疗是CWI早期复发的独立危险因素.Objective To investigate the related factors of early recurrence to cerebral watershed infarction （CWI）.Methods The clinical data of 121 patients with acute CWI were collected,and followed up for 1 month.According to recurrence state,patients were divided into recurrence group and no recurrence group.The related factors of CWI early recurrence were analyzed.Results According to recurrence state,patients were divided into recurrence group （36 cases） and no recurrence group （85 cases）.Compared with no recurrence group,the rates of degree of stenosis ≥ 90 % and expansion treatment,and systolic pressure were significantly decreased; the rates of unstable plaque and active antihypertensive treatment were significantly increased （P 〈 0.05-0.01）.Logistic regression showed that unstable plaque （OR =4.929,95% CI：1.491-16.296,P 〈 0.01）,degree of stenosis ≥ 90% （OR =6.072,95% CI：2.115-17.430,P 〈 0.01） and active antihypertensive therapy （OR =3.840,95% CI：1.418-10.400,P 〈 0.01） were independent risk factors of early recurrence to CWI.Conclusion The unstable plaque,cerebral vascular severe stenosis and antihypertensive treatment are independent risk factors of early recurrence to CWI.

关 键 词：分水岭脑梗死 相关因素 早期复发 

分 类 号：R743.3[医药卫生—神经病学与精神病学]