酒精性肝病与氧化应激  

Alcoholic liver disease and oxidative stress

作　　者：赵雪珂[1] 穆茂[1] 程明亮[1] 

机构地区：[1]贵阳医学院附属医院感染科,贵阳550004

出　　处：《临床肝胆病杂志》2014年第2期118-120,共3页Journal of Clinical Hepatology

摘　　要：酒精性肝病(ALD)是威胁人类健康的重大疾病之一,其发病机制错综复杂。氧化应激性肝损害在其中占有至关重要的地位,如何系统的认识机体的氧化与抗氧化系统在ALD发生发展过程中所扮演的角色,对ALD的防治工作具有一定的指导意义。Alcoholic liver disease（ALD） is a major and serious health threat. The pathophysiology of ALD is very complex and still largely elusive but we do know now that the oxidative stress - induced liver injury plays a critical and definitive role in the pathogenesis of ALD according to the currently accumulated research data. Therefore a comprehensive review of how the cellular oxidation and antioxidant system impacts the process of occurrence and progression of ALD might shed new as well as significant light on our strategy to prevent and treat ALD.

关 键 词：肝疾病 酒精性 氧化应激 综述 

分 类 号：R575.5[医药卫生—消化系统]