海南益智茎叶中有机酸类化学成分  

Chemical Constituents of Organic Acid Part from Stems and Leaves of Alpinia oxyphylla

作　　者：李洪福[1,2] 谭银丰[1,2] 王勇[1,2] 魏娜[1] 李永辉[1,2] 张俊清[1,2] 

机构地区：[1]海南医学院药学院,海口571101 [2]海南省热带药用植物研究与开发重点实验室,海口571101

出　　处：《中国实验方剂学杂志》2014年第6期96-99,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家"十二五"区域基地项目(SQ2010BAJY1411-07-02);海口市重点科技计划项目(ZDXM20110037);海南医学院科研培育基金项目(HY2012-018)

摘　　要：目的：研究海南益智茎叶中有机酸类化学成分.方法：海南益智茎叶用95％乙醇提取后,依次用石油醚、三氯甲烷、乙酸乙酯、正丁醇萃取,对石油醚萃取部位和三氯甲烷萃取部位采用各种色谱方法进行分离、纯化,通过理化性质和波谱分析对分离得到的化合物进行结构鉴定.结果：从海南益智茎叶中分离得到了10个有机酸类化合物,分别鉴定为对羟基桂皮酸（1）,香草酸（2）,原儿茶酸（3）,对羟基苯甲酸（4）,肉豆蔻酸（5）,棕榈酸（6）,β-谷甾醇棕榈酸酯（7）,花生酸（8）,二十二烷酸（9）和二十八烷酸（10）.结论：化合物1 ～ 10均为首次从该植物茎叶中分离得到.Objective：To study the chemical constituents of organic acid in the stems and leaves of Alpinia oxyphylla.Method：The stems and leaves of A.oxyphylla were extracted with 95％ ethanol and then extracted by petroleum ether,chloroform,ethyl acetate,and n-butyl alcohol respectively,the chemical constituents were isolated by using various column chromatorgaphies from petroleum ether and chloroform parts,and their structures were elucidated on basis of physicochemical constants and spectral data analysis.Result：Ten organic acid compounds were obtained and determined to be p-hydroxycinnamic acid （1）,vanillic acid （2）,protocatechuic acid （3）,p-hydroxybenzoic acid （4）,myristic acid （5）,palmitic acid （6）,（-sitosterol palmitate （7）,arachidic acid （8）,docosanoic acid （9）,octacosanoic acid （10）.Conclusion：Compounds 1-10 were obtained from the parts of stems and leaves of A.oxyphylla for the first time.

关 键 词：益智茎叶 有机酸 结构鉴定 

分 类 号：R284.1[医药卫生—中药学]