肝硬化合并自发性腹膜炎患者血清和腹水降钙素原检测的意义  

Clinical significance of detecting levels of serum and ascitic PCT in patients with liver cirrhosis complicating spontaneous bacterial peritonitis

作　　者：谢飞[1] 刘志祥[1] 陈黎[2] 

机构地区：[1]湖北医药学院附属太和医院检验科,湖北十堰442000 [2]湖北医药学院附属太和医院ICU,湖北十堰442000

出　　处：《国际检验医学杂志》2014年第5期525-526,共2页International Journal of Laboratory Medicine

摘　　要：目的通过研究肝硬化合并自发性细菌性腹膜炎(SBP)患者血清和腹水降钙素原(PCT)的变化探讨其在肝硬化合并SBP早期诊断中的价值。方法对92例肝硬化腹水患者应用免疫荧光法测定血清、腹水中PCT并与腹水常规和细菌培养结果进行比较。结果 SBP组及非SBP组患者血清PCT水平明显高于对照组,差异有统计学意义(P<0.05),SBP组血清和腹水PCT水平明显高于非SBP组;血清PCT对腹膜炎诊断的敏感度为89.3%,腹水中PCT对腹膜炎诊断的敏感度为71.4%。结论血清及腹水PCT水平对肝硬化腹膜炎的早期诊断有重要价值且血清PCT具有更高的早期诊断价值。Objective To study the changes of serum and ascitic procalcitonin （PCT ） level in the patients with liver cirrhosis complicating spontaneous bacterial peritonitis （SBP） and to investigate the value in its early diagnosis .Methods 92 patients with cirrhotic and ascites were detected the levels of serum and ascitic PCT by the immunofluorescence method and the detection results were compared with the ascites routine and the bacterial culture results .Results Serum levels of PCT in the SBP group and the non-SBP group were obviously higher than those in the control group ,the difference was statistically significant （P＆lt;0 .05）;Serum and ascitic levels of PCT in the SBP were significantly higher than those in the non-SBP group ;The sensitivity of serum PCT for di-agnosing peritonitis was 89 .3% ,the sensitivity of ascitic PCT for diagnosing peritonitis was 71 .4% .Conclusion The levels of ser-um and ascitic PCT have the important value for the early diagnosis of liver cirrhosis ascites ,moreover serum PCT level has higher value for early diagnosing liver cirrhosis ascites .

关 键 词：降钙素原 肝硬化 腹膜炎 

分 类 号：R575.2[医药卫生—消化系统]