以阿魏酸为指标研究肺热清解口服液的质量标准  

Study on Quality Standard of Feire Qingjie Oral Liquid Based on Ferulic Acid

作　　者：刘佩沂 赖岳晓 田素英[2] 

机构地区：[1]广东省中山市黄圃人民医院,广东中山528429 [2]广东药学院,广东广州510006

出　　处：《现代中药研究与实践》2014年第1期60-62,共3页Research and Practice on Chinese Medicines

基　　金：广东省中山市卫生局科研项目(编号:2009078)

摘　　要：目的研究肺热清解口服液的质量控制方法。方法采用薄层色谱（TLC）法对肺热清解口服液中芦根与川贝进行定性鉴别，采用紫外分光光度法测定肺热清解口服液中阿魏酸的含量。结果样品溶液中的芦根和川贝与其对照药材TLC在相应位置上显相同斑点，阴性对照无干扰；阿魏酸在1．00—6．00ug．mL-1范围内与吸光度呈良好的线性关系，r=0．9997，平均回收率为103．04％，RSD为1．9％（n=6）。结论本方法简便、快捷、准确，可作为控制肺热清解口服液质量的方法之一。Objective To establish the quality control method of Feire Qingjie Oral Liquid. Methods Phragmites communis and Bulbus fritillariae cirrhosae were identified qualitatively by TLC. UV was used to determine the content of ferulic acid. Results The characteristic identification by TLC was distinct and highly specific. The negative control had no interference. Ferulic acid showed a good linear relationship in the range of 1.00-6.00 ug . mL-1, r=0.999 7. The average recovery rate was 103.04%,RSD=1.9%（n=6）. Conclusion This method is convenient, quick, accurate and available for the quality control of Feire Qingiie Oral Liquid.

关 键 词：肺热清解口服液 阿魏酸 薄层色谱法 紫外分光光度法 

分 类 号：R927.11[医药卫生—药学]