微波消解-冷汞发生器-原子吸收光谱法测定中药材中痕量汞的研究  

Determination of trace mercury in Chinese herb medicine by new cold mercury generation- atomic absorption spectrometry with microwave digestion

作　　者：朱晓鹏[1] 张振中[1] 邵爱娟[2] 李振国[3] 宋汉敏[3] 郑子栋[3] 游强[3] 王巨才 

机构地区：[1]郑州大学药学院,郑州450001 [2]中国中医科学院中药研究所,北京100700 [3]河南省食品药品检验所,郑州450003 [4]中华人民共和国海南口岸药品检验所,海口570216

出　　处：《医药论坛杂志》2014年第1期1-3,6,共4页Journal of Medical Forum

基　　金：中华人民共和国科技部科技支撑计划课题(2006BAI21B07)

摘　　要：目的建立微波消解-冷汞发生器-原子吸收光谱法测定中药材中痕量汞的方法。方法用微波消解法对几种常用中药材样品进行前处理,用冷汞发生器-原子吸收光谱法测定其中的痕量汞。结果微波消解过程中,消解试剂选择硝酸+氢氟酸(8∶1)消化效果最佳,汞在浓度为0μg/L^50μg/L范围内线性关系良好,相关系数r=0.9999,方法检出限为0.025μg/L,测定汞30μg/L标准溶液相对标准偏差为1.78%,测定国家一级标准物质人发(GBW09101)相对标准偏差为3.35%,且测定结果与标准含量一致。结论该方法测定中药材中痕量汞安全环保,简单快速,准确灵敏,具有良好的应用前景。Objective To establish a method for determination of trace mercury in Chinese herbal medcine by new cold mercury generation - atomic absorption spectrometry with microwave digestion. Methods After pretreatment by micro- wave digestion system, trace mercury in several common Chinese herbal medicine were determined by cold mercury gen- eration - atomic absorption spectrometry. Results When using the nitric acid ＋ hydrofluoric acid peroxide reagent at the ratio of 8：1 as acid digestion reagent in the digestion process,the samples will be completely digested wide linear rela- tionship was achieved in the range of 0μg/L-50μg/L with relative coefficient of 0. 9999 and the detection limit was 0. 025μg/g with RSD of 1.78% formercury at 30μg/L Trace mercury in the standard reference substance human hair （ GBW09101 ） was determined incording this way. The results were in good agreement with certified value and RSD was 3.35%. Conclusion Determination of trace mercury in Chinese herbal medicine has safe environmental protection,this method is simple, rapid, accurate, sensitive and has a good application prospect.

关 键 词：微波消解 冷汞发生器 原子吸收光普法 中药材 规范 痕量汞 

分 类 号：R284[医药卫生—中药学]