痰细胞学联合支气管镜DNA倍体检测对肺癌的诊断意义  

Diagnostic value of sputum cytology combined with bronchoscopy detection of DNA ploid in lung cancer

作　　者：何敏[1] 邝军[1] 朱建勇[1] 张立波[1] 叶青[1] 

机构地区：[1]湖北医药学院附属人民医院呼吸内科一病区,湖北十堰442000

出　　处：《临床肺科杂志》2014年第4期710-712,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨痰细胞学联合支气管镜DNA倍体检测对肺癌的诊断价值。方法 80例患者行痰细胞学、支气管镜DNA倍体检测。结果 54例确诊为肺癌,痰细胞学检测阳性率29.92%,支气管镜DNA倍体检测阳性率69.87%,两者联合检测阳性率为95.18%;DNA倍体分析与细胞学联合检测灵敏度为98.38%,明显高于DNA倍体分析91.85%及细胞学78.58%(P<0.05)。结论痰细胞学联合支气管镜DNA倍体检测能有效的提高肺癌检测的灵敏度。Objective To investigate the diagnostic value of sputum cytology combined with bronchoscopy detection of DNA ploid in lung cancer. Methods 80 patients were given sputum cytology and bronchoscopy detection of DNA ploid. Results There were 54 cases of lung cancer. The positive rate of sputum cytology was 29.92%, and 69.87% of bronchoscopy detection of DNA ploid. The positive rate of combined detection was 95.18%. The sensitivity of combined detection was 98.38%, which was significantly higher than any single detection （P〈0.05）. Conclusion The combined application of sputum cytology and bronchoscopy DNA ploid can effectively improve the sensitivity of detection of lung cancer.

关 键 词：痰细胞学 DNA倍体检测 肺癌 

分 类 号：R734.2[医药卫生—肿瘤]