体素内无规则运动核磁成像技术在前列腺癌诊断中的价值  

Intravoxel incoherent motion MR imaging for diagnosis of prostate cancer： an evaluation of perfusion fraction and diffusion coefficient

作　　者：曹曙[1] 曹惠霞[2] 胡卫列[3] 

机构地区：[1]第二军医大学研究生院,上海200433 [2]广州军区广州总医院核磁共振室 [3]广州军区广州总医院泌尿外科

出　　处：《中国男科学杂志》2014年第1期25-28,共4页Chinese Journal of Andrology

摘　　要：目的分析体素内无规则运动核磁成像（intravoxel incoherent motion MR imaging，IVIM—MRI）参数与病理诊断的相关性，探讨其在诊断、评估前列腺癌的恶性程度、预后的应用价值。方法分析21例前列腺癌患者IVIM参数弥散系数D及灌注因子^结合病理结果对比良性增生组织与肿瘤组织及中高危组与低危组中之间的区别。结果弥散系数D及灌注因子厂（排除b=800s／mm^2）在良、恶性组织中差异均具有统计学意义（P〈0．05），同时，弥散系数D在中高危组与低危组之间差异也具统计学意义（P〈0．05）。结论IVIM技术有助于前列腺癌的诊断；弥散系数D值有助于对前列腺癌恶性程度的预估。Objective To evaluate the value of intravoxel incoherent motion MR imaging diffusion coefficients （D） and perfusion fractions （f） in the diagnosis of prostate cancer. Methods The clinical and imaging data of 21 patients with prostatic cancer were analyzed retrospectively, including the D values and the f values of the different pathological pattern and the different levels of malignancy. Results There were significant difference in D values andfvalues （exclude b=800s/ mm^2） between the normal and tumor tissues（P〈0.05）. But, between the different levels of malignancy, only the D values had statistical difference（P〈0.05）. Conclusion IVIM shows some advantages in the differential diagnosis of prostatic cancer and accurate quantification of D value will be helpful to determine tumor malignancy.

关 键 词：前列腺癌 磁共振成像 弥散 

分 类 号：R737.25[医药卫生—肿瘤]