特应性皮炎102例食物特应性斑贴试验结果与各临床指标的相关性分析  

The Analysis of the Correlation Between the Results of Atopy Patch Test in Food Allergy and the Clinical Index of 102 AD Patients

作　　者：王兰[1] 李东宁[1] 孙健[1] 闫铁夫[1] 王莉丽[1] 杜红阳[1] 

机构地区：[1]辽宁医学院附属第一医院皮肤性病科,辽宁锦州121000

出　　处：《中国皮肤性病学杂志》2014年第4期362-365,共4页The Chinese Journal of Dermatovenereology

基　　金：辽宁省医学高峰建设工程重点科研项目之过敏性疾病专科项目建设(200930)

摘　　要：目的分析食物过敏原的特应性斑贴试验(APT)结果与特应性皮炎(AD)患者的SCORAD评分、临床分型、血清特异性IgE水平间的相关性。方法选择2010年1月-2012年12月本科门诊确诊的102例AD患者进行食入性过敏原(鸡蛋清、牛奶、黄豆、海虾、小麦)的特应性斑贴试验,同时进行这5种过敏原的血清sIgE测定,分析APT结果与临床各指标的相关性。结果 AD患者中不同严重程度组之间5种食物过敏原的APT阳性率差异均无统计学意义(P>0.05);内源型AD和外源型AD患者的APT阳性率差异均无统计学意义(P>0.05);AD患者血清sIgE水平与APT结果有相关性(P<0.05)。结论食物过敏原APT检测结果与AD患者的SCORAD评分及临床分型均无相关性,但与AD患者血清sIgE水平有相关性。Objective To analyze the correlation between atopy patch test of food allergen and AD patients＇ SCORAD scores, clinical classification and serum specific IgE level. Methods One hundred and two AD subjects selected from undergraduate outpatient service from January 2010 to December 2012 were enrolled in the study of atopy patch test regarding five food allergens （egg, milk ,soybean, prawn and wheat）. All subjects were also tested with specific serum IgE and with the same five food ＇allergens, then the correlation between the results of atopy patch test and AD patients＇various clinical indicators was analyzed. Results There was no statistically significant difference between different groups of SCORAD scores and APT results （ P 〉 0.05 ）. There was no statistically significant difference between APT results of intrinsic AD and extrinsic AD （ P 〉 0.05 ）. But there was significant difference between slgE level and APT results （ P 〈 0.05 ）. Conclusion There is no relevance between results of APT and AD＇s SCORAD scores and clinical classification, but it has relevance with sIgE level.

关 键 词：特应性斑贴试验 特应性皮炎 食物过敏原 SCORAD评分 血清sIgE 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]