对左旋多巴长期治疗帕金森病的评价  

Evaluation of Long-term Treatment with L-dopa for the Patients with Parkinson's Disease

作　　者：蒋雨平[1] 

机构地区：[1]复旦大学附属华山医院神经科,200040

出　　处：《中国临床神经科学》2014年第1期94-97,共4页Chinese Journal of Clinical Neurosciences

摘　　要：很多研究证明长期应用左旋多巴(L-dopa)治疗帕金森病(PD),可明显改善PD患者的症状,而且应该在PD的早期应用适量的左旋多巴进行治疗,以改善患者的早期症状。长期应用左旋多巴治疗PD与长期应用多巴胺受体激动剂对疾病导致的病死率相同。长期应用多巴胺受体激动剂治疗PD的疗效与长期应用左旋多巴相同,前者并未显示出优越性。The present studies showed that in the long-term treatment of Parkinson＇ s disease with L-dopa, it is better to use moderate L-dopa as early as possible, which can alleviate the clinical symptoms. Initial treatment with the dopamine agonist bromocriptine did not reduce mortality. There was no evidence of advantage of dopamine agonist over L-dopa in the long-term treatment of Parkinson＇ s disease.

关 键 词：帕金森病 左旋多巴 治疗 多巴胺受体激动剂 

分 类 号：R742.5[医药卫生—神经病学与精神病学]