磁共振弹性成像评价主动脉壁硬度  

Magnetic resonance elastography in assessment on stiffness of aorta

作　　者：徐磊[1] 王辉[1] 张楠[1] 张兆琪[1] 范占明[1] 吕飚[1] 于薇[1] 

机构地区：[1]首都医科大学附属北京安贞医院医学影像科,北京100029

出　　处：《中国医学影像技术》2014年第3期366-368,共3页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金(81271542;81171336);北京市优秀人才项目(2011D003034000030);科技部国际交流合作基金(2010DFB300 40)

摘　　要：目的探讨磁共振弹性成像(MRE)评价主动脉壁硬度的可行性。方法采用MRE技术观察5名健康志愿者的腹主动脉,将气动震动装置置于前腹壁,使其产生60Hz低频率机械波,经腹部传播至腹主动脉,并在主动脉管腔内产生机械波传播;以梯度回波为基础的MRE序列对主动脉内传播的机械波进行成像。结果机械波在腹主动脉管腔内沿腹其长轴传播良好;通过测量机械波波长,初步估算得出腹主动脉的硬度。结论 MRE技术对评价主动脉壁硬度具有一定可行性。Objective To investigate the feasibility of magnetic resonance elastography （MRE） technique in evaluation on the mechanical properties of aortic wall in vivo. Methods MRE was performed to observe abdominal aorta in 5 healthy male volunteers. A passive driver was positioned against anterior abdominal wall. The passive driver produced longitudinal vibrations, which transmitted into abdomen and produced mechanical wave propagation within abdominal aorta. Low amplitude mechanical waves at 60 Hz were generated in the abdomen during imaging. A gradient-echo MRE sequence was used to acquire images showing mechanical wave propagation within abdominal aorta. Results The propagating wave images were well visualized within the lumen of abdominal aorta in all 5 subjects. The waves propagated longitudinally along the abdominal aorta. The stiffness of aortic wall was evaluated by estimating wavelength. Conclusion MRE technique has potential for noninvasively assessing stiffness of aorta.

关 键 词：磁共振成像 主动脉 硬度 

分 类 号：R543.1[医药卫生—心血管疾病] R445.2[医药卫生—内科学]