绝对时相收缩期采集降低心房颤动患者冠状动脉CT成像辐射剂量的研究  

Absolute phase acquisition versus relative phase acquisition for dual source CT coronary angiography in patients with atrial fibrillation

作　　者：徐磊[1,2] 杨琳[1,2] 范占明[1,2] 张兆琪[1,2] 吕飙[1,2] 于薇[1,2] 

机构地区：[1]首都医科大学附属北京安贞医院 [2]北京市心肺血管疾病研究所影像科,北京100029

出　　处：《心肺血管病杂志》2014年第1期84-88,共5页Journal of Cardiovascular and Pulmonary Diseases

基　　金：北京市优秀人才项目(2011D003034000030);北京市卫生系统高层次卫生技术人才资助项目

摘　　要：目的：研究绝对时相收缩期采集在心房颤动患者冠状动脉CT血管造影（CTA）的可行性,并与相对时相采集对照.方法：连续入组92例持续心房颤动患者,其中A组46例采用绝对时相收缩期采集（R波后200～400ms）,B组46例采用相对时相收缩期采集（R-R间期：30％ ～ 50％）.对两组扫描的冠状动脉分别做图像处理.比较两组的图像质量和辐射剂量.结果：A组冠状动脉段图像质量总体评分为（1.56±0.25）,B组为（1.62±0.28）,两组间差异无统计学意义（P =0.283）.两组之间可诊断的冠状动脉段比率差异无统计学意义（P =0.785）.A组有效剂量5.76（3.20,8.63） mSv;B组有效剂量9.27（4.74,12.65）mSv,两组间有效剂量差异有统计学意义（P =0.001）.绝对时相采集比相对时相采集降低辐射剂量约38％.结论：在心房颤动患者绝对时相收缩期采集具有可行性,该方案比相对时相采集显著降低辐射剂量,而不影响图像质量.Objective：To investigate the feasibility of absolute phase systolic acquisition for coronary CT angiography （CCTA） in patients with atrial fibrillation （AF） with comparison to relative phase acquisition.Methods：Ninety-two patients with persistent AF were enrolled in the study,46 patients were scanned with absolute phase systolic acquisition （200-400 ms after the R wave） and another 46 were studied by relative phase systolic acquisition （30％-50％ of the R-R interval） for CCTA using the second generation dual source CT （DS-CT）.The imaging quality and radiation dose were compared between the two protocols.Results：There was no significant difference in overall image quality between the two groups （P =0.283）.Median effective doses of absolute phase acquisition and relative phase acquisition were 5.76 （3.20,8.63） mSv and 9.27 （4.74,12.65） mSv respectively （P =0.001）,showing that absolute phase acquisition reduced radiation dose by 38％ compared with that of relative phase acquisition.Conclusion：In patients with AF,absolute phase systolic acquisition is feasible in DS-CT coronary angiography,and can decrease radiation exposure by approximately 35％ compared with relative phase acquisition,while preserving image quality.

关 键 词：体层摄影术 X线计算机 冠状动脉 辐射剂量 心房颤动 

分 类 号：R54[医药卫生—心血管疾病]