疏风通络止痛中药治疗偏头痛的临床观察  

Clinical observation of Shufeng Tongluozhitong TCM in treatment of migraine

作　　者：李岚生[1] 

机构地区：[1]广东省珠海市人民医院海关医务所,519000

出　　处：《中华全科医学》2014年第4期631-632,共2页Chinese Journal of General Practice

摘　　要：目的观察疏风通络止痛中药对偏头痛的临床治疗效果。方法将144例偏头痛患者随机分为2组,每组72例,对照组脱落2例,治疗组给予疏风通络止痛中药口服,对照组给予盐酸氟桂利嗪胶囊口服,比较2组患者临床疗效,测定并比较2组患者治疗前后血清中血浆内皮素(ET)、一氧化氮(NO)浓度、头部主要供血动脉血流速度。结果治疗组临床疗效优于对照组:Z=-3.697,P<0.05;2组患者治疗后血浆ET值降低(P<0.05),治疗组低于对照组:t=3.5759,P<0.05;2组患者治疗后血浆ON值升高(P<0.05),治疗组高于对照组:t=2.3118,P<0.05;治疗后治疗组大脑前动脉(ACA)、大脑中动脉(MCA)、大脑后动脉(PCA)和椎、基底动脉(VA、BA)血流速度低于对照组,t值分别为4.2084、8.7753、7.3710和5.8667,P<0.05,差异有统计学意义。结论疏风通络止痛中药治疗偏头痛疗效确切,安全性高,可作为偏头痛首选的治疗方法。Objective To observe the clinical therapeutic effect of Shufeng Tongluozhitong TCM in the treatment of mi- graine. Methods All 144 patients with migraine were randomly divided into two groups,72 cases in each group,two ca- ses fell off from the control group, the treatment group was treated with Shufeng Tongluozhitong TCM, while the control group were taken flunarizine hydrochloride capsules. The clinical curative effect of the two groups was compared. The con- centration of Et and NO o before and after the treatment, and the blood flow velocity of major artery were also determined and compared. Results Clinical curative effect of the treatment group was better than the control group （ Z = - 3. 697, P 〈0.05 ;The plasma ET value of the patients decreased in both groups（ P 〈 0.05 ） ,the treatment group was lower than the control group ： t = 3. 5759, P 〈 0.05 ; The plasma ON levels elevated in two groups （ P 〈 0.05 ）, the treatment group was higher than the control group ：t = 2.3118, P 〈 0.05 ;The ACA, MCA, PCA and VA, BA blood flow velocity of the treatment group was lower than that of the control group, the t value was 4. 2084,8. 7753,7. 3710 and 4. 2084, P 〈 0.05, the differ- ence was statistically significant. Conclusion Shufeng Tongluozhitong TCM is effective and safe for migraine, and can be used as the preferred in the treatment of migraine.

关 键 词：疏风通络止痛 中药 偏头痛 

分 类 号：R747.2[医药卫生—神经病学与精神病学] R289.56[医药卫生—临床医学]