阑尾杯状细胞类癌的病理特征与治疗  

The pathological features and treatment of goblet cell carcinoid of appendix

作　　者：王卓才[1] 冯晓冬[2] 黄小让[3] 陈炳旭[2] 

机构地区：[1]广州军区广州总医院病理科,广州510010 [2]广州金域医学检验中心病理部,广州510330 [3]广州军区广州总医院综合科,广州510010

出　　处：《广东医学》2014年第4期517-519,共3页Guangdong Medical Journal

摘　　要：目的 探讨阑尾杯状细胞类癌（GCC）的病理特征和治疗.方法分析8例阑尾GCC的病理特征及治疗特点.结果 本组阑尾GCC患者年龄（53.5±12.3）岁,男5例,女3例,常表现为阑尾炎,少数无症状或右下腹肿块.多因阑尾炎或其他手术偶然诊断.肿瘤浸润阑尾肌层或浆膜层不形成肿块.治疗首选手术,依据肿瘤大小和浸润转移范围选择阑尾切除和（或）半结肠切除术,〉50岁女性主张全子宫双侧输卵管卵巢一并切除.随访26~79个月,平均（53.6±2.3）个月,未见复发转移.结论 阑尾GCC罕见,不形成明显肿块,临床无特异性特征.治疗依据肿瘤部位、大小、浸润和转移范围决定手术和（或）化疗方案.预后大多良好.Objective To investigate the pathological features and treatment of goblet cell carcinoid （GCC） of appendix. Methods Pathological diagnosis and treatment of 8 cases of GCC of appendix were analyzed. Results The mean age of patients with appendix GCC was （53.5±12.3） years, including 5 male cases and 3 female cases. Appendicitis like symptoms was most common observed, and a few with no symptom or right lower quadrant mass. Accidental diagnosis was usually made in appendicitis or other surgery. Myometrial or serosal invasion in appendix was observed with no lumps. Surgical treatment was the primary choice; and based on tumor size and metastasis range, selected appendectomy and/or right hemicolectomy were selected, while bilateral salpingo-oophorectomy was also advocated in females over 50 years old. During the follow-up of （53.6±2.3） months, no recurrence was reported. Conclusion Appendix GCC is rare with occult symptoms and no significant mass. Treatment is selected based on tumor location, size, invasion and metastasis range, with fair prognosis.

关 键 词：阑尾杯状细胞类癌 临床病理 治疗 

分 类 号：R735.36[医药卫生—肿瘤]