子宫颈液基细胞学检查TBS诊断的价值  

Clinical value of cervical liquid cytology test and the Bethesda System diagnosis

作　　者：马俊如[1] 唐国珍[1] 樊元春[2] 张国宾[2] 

机构地区：[1]成都医学院第一附属医院妇产科,四川成都610500 [2]成都医学院第一附属医院病理科,四川成都610500

出　　处：《中国生育健康杂志》2014年第2期126-128,共3页Chinese Journal of Reproductive Health

基　　金：四川省卫生厅资助课题（100106）

摘　　要：目的 探讨液基细胞学诊断宫颈病变的价值. 方法 回顾性分析383例宫颈宫颈薄层液基细胞学（thin prep cytology test,TCT）检查结果,行TBS细胞分类学诊断.以宫颈活检和术后组织病理学为金标准,对照分析TCT检查结果的符合率. 结果 TCT阳性、阴性分别为39.4％和59.6％.TCT检查结果中,NILM、ASC-US、ASC、LSIL、HSIL、SCC和AC阳性预测值分别为84.5％、73.1％、62.5％、37.5％、92.3％、100.0％和100.0％.TCT的灵敏度为74.6％,特异度为81.3％,符合率为78.9％,与组织病理学结果一致. 结论 液基细胞学检查在筛查宫颈高级别病变中有较高的符合率,联合阴道镜下组织活检和病理学检查能够更好地筛查宫颈癌及癌前病变.Objective To examine the value of thin prep cytology test （TCT） combined with the results of cervical biopsy under colposcopy and tissue pathology in the diagnosis of cervical lesion.Methods Retrospective analysis of 383 cases examined with TCT and the Bethesda System （TBS） diagnosis.The diagnoses of TCT with cervical biopsy under colposcopy or histopathological examination after surgery were compared.Results There were 36 cases （15.5％） with positive results among the 232 NILM cases,57 cases （73.1％） with positive results among the 78 ASC-US cases,30 cases （62.6％） with positive results among the 48 ASC cases,3 cases （37.5％） with positive results among the 8 LSIL cases,and 12 cases （92.3％） with positive results among the 13 HSIL cases; all 3 SCC cases were positive,and 1 AC case was positive.High grade TCT had high coincidence rate with the histopathological results.Conclusion High grade TCT had high coincidence rate with histopathological examinations.TCT can be better used to screen cervical cancer and precancerous lesion along with biopsy and histopathology under colposcopy.

关 键 词：液基细胞学 宫颈病变 阴道镜 病理活检 

分 类 号：R737.3[医药卫生—肿瘤]