黄烷酮的合成研究进展  

Research Progress in Synthesis of Flavanones

作　　者：杨柳阳[1] 朱观明 

机构地区：[1]浙江工业大学药学院,浙江杭州310014

出　　处：《合成化学》2014年第2期272-280,共9页Chinese Journal of Synthetic Chemistry

基　　金：浙江省自然科学基金资助项目(Y4100558)

摘　　要：黄烷酮是含有二氢色原酮骨架结构的黄酮类化合物。本文梳理了合成黄烷酮的文献,总结了其合成方法,按原料结构特征分类论述其合成方法:即从黄烷酮衍生物经官能团变换合成黄烷酮;查耳酮经氧-Michael加成合成黄烷酮;非查耳酮结构构建合成黄烷酮。重点论述了第二类合成方法。参考文献82篇。Flavanones exist with the structure of 4-（2H）-chromanone and are kinds of flavonoids. In this review, the synthetic methods of flavanones are summarized based on the reported literatures ac- cording to the structure of starting materials, namely method via function group transformation from the flavanone derivatives, classical method from chalcones via oxa-Michael addition and method through the construction of other structure instead of chalcones. The second method were highlighted here. 82 references were cited.

关 键 词：黄烷酮 4-二氢黄烷酮 关环 氧-Michael加成 合成 综述 

分 类 号：O625.42[理学—有机化学]