颈及胸上段食管癌同步加量调强放疗的剂量学研究  

Dosimetric study of simultaneous integrated boost intensity-modulated radiotherapy for cervical and upper thoracic part esophageal carcinoma

作　　者：蒋俊[1] 权循凤[1] 洪浩[1] 李锐[1] 

机构地区：[1]安徽医科大学第一附属医院肿瘤放疗科,合肥230022

出　　处：《安徽医科大学学报》2014年第3期392-394,共3页Acta Universitatis Medicinalis Anhui

基　　金：安徽省教育厅自然科学重点项目(编号:KJ2010A170)

摘　　要：对7例颈及胸上段食管癌患者分别设计3、5、7野3种同步加量调强放疗的设野计划,比较3种计划间靶区和危及器官的剂量学差异。结果显示3野计划的靶区覆盖率、适形指数和均匀性指数明显劣于5野和7野。7野计划中双肺V5明显大于3野和5野。表明3野计划即可使颈及胸上段食管癌的治疗靶区得到足够的照射剂量,但均匀性及适形度差,5野计划可使靶区获得较为理想的剂量分布,可作为临床首选。Seven cervical part and upper thoracic part esophageal carcinoma patients were respectively designed for 3 ,5 ,7 fields in simultaneous integrated boost intensity-modulated radiotherapy plans to compare the differences in target and organ at risk dose. Results revealed that the target area dose coverage,conformity index and homogeneity index in 3 fields plans were inferior to 5 fields and 7 fields plans. Moreover, the both lung V5 in 7 fields plan was greater than 5 fields and 3 fields plans. The target area could receive sufficient dose in 3 fields plan, but the uni-formity and conformity were unsatisfied. 5 fields plan made the target area receive ideal dose distribution, which showed 5 fields plan was the first choice in clinic.

关 键 词：食管癌 同步加量 调强放疗 剂量学 

分 类 号：R730.55[医药卫生—肿瘤]