表遗传学几个重要问题的述评  

Several important questions of epigenetics

作　　者：薛开先[1] 

机构地区：[1]江苏省肿瘤防治研究所遗传学研究室,南京210009

出　　处：《遗传》2014年第3期286-294,共9页Hereditas（Beijing)

摘　　要：表遗传学(Epigenetics)是研究没有DNA序列变化的、可遗传的表达改变。表遗传学的发展弥补了传统遗传学的不足,促进了遗传学的发展。表遗传学与传统遗传学之间的关系有如阴阳,它们既相区别,又彼此协同参与发育和进化等重要生物学过程的调控,构成了遗传学密不可分的两个组成部分。文章讨论了表遗传学的定义、研究内涵和中文译名等问题。Epigenetics is the study of heritable changes in gene expression that occurs without a change in DNA sequence. The development of epigenetics makes up for the insufficiency of classic genetics and promotes the development of genetics. The interrelationship between epigenetics and genetics is like a yin-yang, which are different from each other, and cooperatively take part in regulation of critical biological processes of development and evolution, etc. They constitute the two inseparable parts of genetics. The definition, research connotation and Chinese translation of epigenetics are also discussed.

关 键 词：表遗传学 传统遗传学 发育 进化 

分 类 号：R730.2[医药卫生—肿瘤]