早期显微手术夹闭治疗前交通动脉瘤167例及其预后影响因素分析  

Analysis of prognoses and factors related to them in 167 patients with anterior communicating artery aneurysms undergoing early microsurgical clipping

作　　者：周济[1] 易良[1] 许民辉[1] 

机构地区：[1]第三军医大学大坪医院神经外科,重庆400042

出　　处：《中国临床神经外科杂志》2014年第3期142-144,共3页Chinese Journal of Clinical Neurosurgery

摘　　要：目的分析早期(动脉瘤破裂后72 h内)显微手术夹闭治疗前交通动脉瘤患者的预后影响因素。方法回顾性分析我科2008年12月至2012年3月收治的167例早期行手术夹闭治疗的前交通动脉瘤破裂出血患者的临床资料,采用单因素及多因素Logistic回归分析与预后相关的危险因素。结果多因素Logistic回归分析结果示Hunt-Hess分级、改良Fisher分级、Graeb评分、症状性血管痉挛、吸烟、肺部感染共6个指标是影响前交通动脉夹闭术后患者预后的独立危险因素。结论显微手术夹闭治疗前交通动脉瘤患者的预后受到多种因素的影响,早期干预这些因素,能提高前交通动脉瘤的手术效果。Objective To investigate the factors related to the prognoses of patients with anterior communicating artery （ACoA） aneurysms undergoing early microsurgical clipping in order to reduce the morbidity and mortality. Methods The clinical and imaging data of 167 patients with ACoA aneurysms undergoing microsurgical clipping within 72 hours after the rupture were retrospectively analyzed. The risk factors related to the prognoses were analyzed by single factor and muhivariable factors Logistic regression analysis. Results The muhivariable factors Logistic regression analysis showed that the independent risk factors related to the prognoses included Hunt-Hess scale, modified Fisher scale, Graeb score, symptomatic vasospasm, smoking and pulmonary infection in the patients with ACoA aneurysms undergoing microsurgery. Conclusion The curative effects of microsurgical clipping on the ACoA aneurysms may be enhanced by the early prevention and treatment of the above-mentioned factors related to the prognoses.

关 键 词：前交通动脉瘤 显微手术 预后 

分 类 号：R743.9[医药卫生—神经病学与精神病学] R651.11[医药卫生—临床医学]