MRI动态增强、^(18)F-FDG-PET/CT显像对鼻咽癌放疗后复发与纤维化早期诊断的临床价值  

Clinical Value about MRI Dynamic Enhancement,^(18)F-FDG PET/CT Imaging Applied to Early Diagnosis of Recurrent and Fibrosis of Nasopharyngeal Carcinoma after Radiotherapy

作　　者：周美英[1] 傅明[1] 万世恒[1] 

机构地区：[1]广东省东莞市人民医院,广东东莞523059

出　　处：《中国医学创新》2014年第6期34-36,共3页Medical Innovation of China

基　　金：东莞市科研项目(201110515000316)

摘　　要：目的:分析MRI动态增强与18F-FDG-PET/CT在鼻咽癌放疗后早期鉴别诊断复发以及纤维化中的价值。方法:选取2005年8月-2011年8月收治的鼻咽癌患者中,放疗后疑出现复发的患者37例,均分别行MRI动态增强与18F-FDG-PET/CT检查,对比两种检测方式的敏感性、特异性、准确性以及检测费用。结果:MRI检测敏感性93.8%,特异性95.5%,准确性94.9%;PET/CT检测敏感性87.5%,特异性91.3%,准确性90.2%;MRI检测敏感性更高(P<0.05);在特异性和准确性上差别不显著,且在检测费用上比较差异无统计学意义(P>0.05)。结论:MRI动态增强与18F-FDG-PET/CT在鼻咽癌放疗后早期鉴别诊断复发以及纤维化中均有一定价值,但同时均有局限性;联合应用利于诊断价值的提高。Objective：To analyze the value about MRI dynamic enhancement,18F-FDG PET/CT imaging applied to early diagnosis of recurrent and fibrosis of nasopharyngeal carcinoma after radiotherapy.Method：37 patients with nasopharyngeal carcinoma and in suspected recurrence after radiotherapy were chosen from August 2005 to August 2011,all were tested by MRI dynamic enhancement and 18F-FDG PET/CT imaging,then compared sensitivity,specificity,accuracy and the test fee of the two kinds of detection methods.Result：The detection sensitivity of the MRI was 93.8%,the specificity was 93.8% and the accuracy was 95.5%;and the detection sensitivity of the PET/CT was 87.5%,the specificity was 91.3% and the accuracy was 90.2%;the detection sensitivity of MRI was higher（P〈0.05）;there had no significant differences on the specificity and accuracy,and there was no significant difference on the test fee（P〉0.05）.Conclusion：There has certain value about MRI dynamic enhancement,18F-FDG PET/CT imaging applies to early diagnosis of recurrent and fibrosis of nasopharyngeal carcinoma after radiotherapy,but all have limitations meanwhile;the diagnostic value can improve by joint application.

关 键 词：MRI ^18F-FDG-PET CT 鼻咽癌 复发 纤维化 

分 类 号：R739.63[医药卫生—肿瘤]