右旋美托咪定用于小儿腭裂修复术全麻后苏醒期躁动的影响  

Effect of Dexmedetomidine on awakening period of restlessness after gen-eral anesthesia in pediatric palatorrhaphy

作　　者：施巍[1] 陈志峰[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院麻醉科,上海200011

出　　处：《中国医药导报》2014年第6期69-71,共3页China Medical Herald

基　　金：上海交通大学医学院附属第九人民医院院内课题(编号YJ2011A10)

摘　　要：目的探讨右旋美托咪定对小儿腭裂修复术全麻后苏醒期血流动力学及麻醉苏醒的影响。方法将择期行腭裂修复手术的60例患儿随机分为观察组及对照组,各30例,两组患儿麻醉诱导后均行七氟醚吸入麻醉维持,观察组同时应用1μg/(kg·h)右旋美托咪定持续泵入维持,对照组仅给予同等容积的生理盐水持续泵入维持。结果观察组心率、二氧化碳分压、躁动评分、缝合口出血发生率与对照组相比差异有统计学意义(P<0.05)。结论术中对小儿腭裂修复术患儿应用右旋美托咪定可减少患儿麻醉后苏醒期的躁动,有利于血流动力学平稳,有助于患儿预后。Objective To investigate the influence of Dexmedetomidine on the hemodynamics and anesthesia recovery during awakening period after general anesthesia after cleft palate repair therapy.Methods 60 cases of cleft palate children who received repair surgery were divided into two groups randomly and each group contained 30 cases,children of both groups were provided Sevoflurane to maintain the anesthesia after the induction.Children in observation group received 1 μg/（kg ·h） Dexmedetomidine and children in observation group received normal saline pumping to maintain.Results The HR,PaCO2,children agitation score and the occurrence rate of seal bleeding compared with the control group,the differences were statistically significant （P 〈 0.05）.Conclusion The application of Dexmedetomidine on cleft palate children during recovery surgery reduces restlessness when they wake up after the anesthesia.It does well in hemodynamic stability and helps the prognosis of children.

关 键 词：右旋美托咪定 小儿 腭裂 全身麻醉 苏醒期躁动 

分 类 号：R782.2[医药卫生—口腔医学]