喉部分切除术治疗喉肿瘤的预后及影响因素分析  

Prognostic efficacy and influencing factors of partial laryngectomy for laryngeal cancer

作　　者：高盛宏 张俊[1] 孙岩[1] 燕志强[1] 

机构地区：[1]解放军第97医院耳鼻咽喉头颈外科,江苏徐州221004

出　　处：《临床军医杂志》2014年第2期189-191,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨喉部分切除术治疗喉肿瘤的预后及影响因素。方法选择我院行喉部分切除术治疗喉肿瘤患者140例,从手术日起对患者进行跟踪随访,随访时长为5年,并对患者的性别、年龄、部位、TNM分期、病理分级、肿瘤大小、喉部分切除术式、淋巴结转移情况以及吸烟、饮酒史等10个因素进行分析。结果 140例患者中有3例失访,随访率为97.9%,患者1、3年及5年生存率分别为97.1%,75.7%和67.1%。单因素分析显示原发部位、分期、病理分级、肿瘤大小、淋巴结转移、吸烟史对喉肿瘤预后有影响,多因素分析显示原发部位、淋巴结转移情况、分期以及吸烟史是影响术后患者生存率的重要因素。结论影响喉肿瘤预后的重要因素为:肿瘤的原发部位、淋巴结转移情况、TNM分期及吸烟史。Objective To study the prognostic efficacy and influencing factors of partial laryngectomy for treatment of laryngeal cancer. Methods A total of 140 patients who had undergone laryngeal partial resection in our hospital were enrolled in. They were followed up for five years. Analysis was carried out via 10 factors including gender, age, site, TNM staging, pathological grade, size, way to partial laryngectomy, lymph node metastasis, smoking history and drinking history. Results In the 140 patients, the follow-up rate was 97.9% （three ones were lost） , and 1-year, 3-year and 5-year survival rates were 97.1% , 75.7% and 67.1% , respectively. Univariate analysis showed that primary site, stage, histological grade, size, lymph node metastasis and smoking history affected the prognosis of laryngeal cancer. Multivariate analysis showed that acting as significant factors, primary site, lymph node metastasis, stage and smoking history affected the postoperative suivival rate. Conclusion The key factors influencing the prognosis of laryngeal cancer are primary site, lymph node metastasis, TNM stage and smoking history.

关 键 词：喉肿瘤 喉部分切除术 影响因素 生存率 

分 类 号：R739.65[医药卫生—肿瘤]