肺多形性癌的影像表现与临床病理对照分析  

Pleomorphic carcinoma of the lung: comparison of image features and pathologic findings

作　　者：赵艳娥[1] 周长圣[1] 胡裕效[1] 张龙江[1] 卢光明[1] 

机构地区：[1]南方医科大学南京临床学院(南京军区南京总医院)医学影像科,210002

出　　处：《国际医学放射学杂志》2014年第2期103-105,共3页International Journal of Medical Radiology

基　　金：国家自然科学基金青年基金项目(81201072)

摘　　要：目的 回顾性分析经病理证实的肺多形性癌病人的影像表现,并与病理进行对照分析.方法 共21例病人纳入研究,女3例,男18例.年龄41～79岁,平均（60.3±9.7）岁.由2名高年资胸部放射诊断主任医师共同进行回顾性阅片,分析的内容包括肿瘤的大小、位置、形态、密度,肺门和纵隔淋巴结以及胸膜或胸壁的受侵及情况.结果 CT平扫,肿瘤CT值和邻近肌肉CT值相似,16例病人有肿瘤侵犯胸膜.16例（76.2％）病人的肿瘤位于肺外周.增强CT扫描,肿瘤呈迅速和持久的轻至中度均匀或不均匀强化.CT增强扫描显示,肿瘤的低密度区域的病理结果为坏死、出血.结论 肺多形性癌好发于老年男性,CT表现特征是肿瘤多位于肺外周、体积较大,肿瘤容易坏死,且易侵犯胸膜.Objective To retrospectively evaluate computed tomographic （CT） features ofpleomorphic carcinoma of the lung and to compare these features with pathologic findings.Methods Twenty-one patients （twenty men,eight women; mean age,60.3 ±9.7 years; range,41-79 years） with pleomorphic carcinoma were selected from our hospital.Two radiologists retrospectively reviewed CT features,which included size and location of tumor,attenuation values and lymph nodes in hilum and mediastinum,and invasion of pleura and chest wall.Results On unenhanced CT scans,attenuation of the tumor was similar to that of the surrounding muscle.Invasion of pleura and chest wall was noted in sixteen patients.Tumors were located at the lung periphery in sixteen patients （16.2％）.On contrast enhanced CT scans,lesions showed homogeneous or non-homogeneous enhancement.Low-attenuation areas on contrast-enhanced CT scans were found correspond to areas of myxoid degeneration,necrosis,or hemorrhage in pathologic specimens.Conclusion Pleomorphic carcinomas of the lung often occurs in elderly males.The CT features of pleomorphic carcinomas include peripheral mass,frequent necrosis and pleural invasion.

关 键 词：肺 多形性癌 肿瘤 病理 影像 

分 类 号：R734.202[医药卫生—肿瘤]