NT-proBNP和Hcy检测在脑卒中患者中的研究  

Study on NT-proBNP and Hcy detection in stroke patients

作　　者：汪欣[1] 赵素萍[2] 吴旋[1] 蔡梅玉[1] 

机构地区：[1]福建中医药大学附属康复医院检验科,福建福州350003 [2]福建省第二人民医院检验科,福建福州350003

出　　处：《国际检验医学杂志》2014年第6期669-670,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨N-末端脑钠肽前体(NT-proBNP)和同型半胱氨酸(Hcy)在监测脑卒中梗死面积大小和病程进展情况中的变化。方法选择101例脑卒中住院患者和100例对照组分别测定NT-proBNP和Hcy并分别进行比较。结果 NT-proBNP和Hcy在梗死1组、梗死2组、梗死3组与对照组比较差异有统计学意义(P<0.05);在急性期组、亚急性期组、慢性期组的NTproBNP和Hcy水平与对照组比较差异有统计学意义(P<0.05)。结论 NT-proBNP和Hcy可作为预测脑卒中病程的两项指标,二者的联合检测可作为脑梗死面积大小和病程进展情况的监测指标。Objective To study the change of N-terminal pro-brain natriuretic peptide （NT-proBNP） and homocysteine（Hcy） for monitoring the infarct size and the progress of disease in stroke. Methods 101 stroke inpatients and 100 healthy people as the control were selected and detected NT-proBNP and Hcy. The detection results were compared. Results Compared with the control group, NT-proBNP and Hcy in the infarct group 1,2 and 3 had statistical differences （P〈0.05） ;Compared with the control group, which in the acute stage,subacute stage and chronic stage groups had statistical differences （P〈0.05）. Conclusion NT-proBNP and Hcy can be used as two indicators in predicting the progress of stroke. The combination detection of NT-proBNP and Hcy can he used as the monitoring indicators of the infarct size and the progress of disease in stroke.

关 键 词：利钠肽 脑 半胱氨酸 卒中 

分 类 号：R743.3[医药卫生—神经病学与精神病学]