无创产前基因检测技术的临床应用价值  

Evaluate the effectiveness of noninvasive prenatal testing

作　　者：赵晓曦[1] 苏日娜[1] 谷孝月 武艾宁[1] 于荣鑫 

机构地区：[1]内蒙古医科大学附属医院妇产科,呼和浩特010050

出　　处：《中华临床医师杂志（电子版）》2013年第23期284-287,共4页Chinese Journal of Clinicians(Electronic Edition)

基　　金：内蒙古自然科学基金(2010MS1103);笹川医学奖学金同学会科研启动金(124)

摘　　要：应用母血中胎儿游离的DNA检测胎儿非整倍体技术已开始应用于临床,这一技术与传统的产前筛查和诊断技术相比,具有无创、快速、准确等优点,它是产前筛查和诊断领域的一次革命。本文通过对比分析现有研究资料,评估无创产前基因检测技术在临床应用价值。Recently, noninvasive prenatal testing （NIPT） via sequencing of maternal plasma cell-free DNA has already translated to clinical care. This technique is noninvasive, quick, correct, compared with conventional screening and diagnosis. NIPT for aneuploidy using cell-free in maternal plasma is revolutionizing prenatal screening and diagnosis. The purpose of this paper is to evaluate the effectiveness of noninvasive prenatal testing.

关 键 词：无创产前基因检测 胎儿染色体病 高通量测序 

分 类 号：R714.5[医药卫生—妇产科学]