儿童颅内室管膜瘤手术后放射治疗的临床分析  

Postoperative radiotherapy for pediatric intracranial ependymomas: a report of 18 cases

作　　者：宋丽楠[1] 孙保锦[1] 陈力[1] 陈怡东[1] 蒋静[1] 侯栋梁[1] 房彤[1] 

机构地区：[1]首都医科大学附属北京世纪坛医院放射治疗科,北京100038

出　　处：《中国肿瘤临床与康复》2014年第3期313-315,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨儿童颅内室管膜瘤的临床特点和治疗转归。方法回顾性分析2010年8月至2012年8月收治的经病理证实的18例儿童颅内室管膜瘤术后放射治疗患者的临床资料，观察疗效并结合文献进行分析。结果男15例，女3例，年龄3～13岁（中位年龄5岁）。中位随访27个月，KPS评分≥80分者14例，KPS评分60—80分者4例。术后复发4例，其中3例死亡。未观察到严重的放射治疗副作用。结论手术是室管膜瘤的首选治疗方法，部分切除和间变性室管膜瘤患者，术后放射治疗是最重要的辅助手段；室管膜瘤常规行局部放射治疗，治疗失败的主要原因为原位复发。Objective To evaluate the clinical characters and treatment results of pediatric in- traeranial ependymomas （EPs）. Methods From August 2010 to August 2012, 18 pediatric patients of postoperative intracranial EPs were treated with radiation therapy （RT） in our department. The outcome was observed and analysed. Results At the endpoint of the follow-up period, four cases were observed of re- currence, of which three cases were died. No severe radiotherapy complications occurred. Conclusions Surgery is the major treatment method, while adjuvant radiotherapy is important for subtotal resection and anaplastic EPs patients.

关 键 词：儿童 室管膜瘤 放射治疗 预后因素 

分 类 号：R739.41[医药卫生—肿瘤]