神经内科门诊神经病理性疼痛患者临床调查  

Clinical survey on neuropathic pain in neurological outpatient department

作　　者：魏博[1,2] 邵燕琪[3] 毛善英[2] 丁美萍[2] 

机构地区：[1]绍兴人民医院神经内科,浙江绍兴312000 [2]浙江大学医学院附属第二医院神经内科,浙江杭州310009 [3]浙江省人民医院神经内科,浙江杭州310014

出　　处：《浙江大学学报（医学版）》2014年第1期89-93,共5页Journal of Zhejiang University(Medical Sciences)

摘　　要：目的:了解神经内科门诊就诊的神经病理性疼痛(NP)患者的病因、年龄、生活质量和情绪状况,分析生活质量及焦虑情绪与疼痛程度的关系。方法:收集浙江大学医学院附属第二医院神经内科门诊的NP患者106例,对患者进行一般状况、疼痛病因、用药情况等方面调查,并作SF-36生活质量量表和汉密尔顿焦虑量表(HAMA)评定。结果:NP患者平均年龄为(57.3±16.4)岁;其中,三叉神经痛(23.6%)、神经根痛(21.7%)、带状疱疹后神经痛(13.2%)最为常见。患者的生活质量影响程度依次为生理职能、躯体疼痛、情感职能、一般健康状况、生理功能、精力、精神健康、社会功能;躯体疼痛与生命质量各维度Pearson相关系数均具有统计学意义(P<0.05)。西药(45.3%)为医生最常用治疗方法。结论:NP以老年患者为多见,三叉神经痛、神经根痛、带状疱疹后神经痛最为常见,严重影响患者生活质量,合理规范的药物治疗能有效控制疼痛。Objective： To survey the features and its impact of neuropathic pain in neurological outpatients. Methods： A total of 106 patients with neuropathic pain were selected from Neurology Clinic of the Second Affiliated Hospital of Zhejiang University.General status instrument, SF-36 Quality of Life Scale and Hamilton Anxiety Scale （HAMA） were used in the survey. Results： Trigeminal neuralgia （23.6%） ,nerve root pain （21.7%）, and post-herpetic neuralgia （ 13.2% ） were the most common causes of neuropathic pain. The sequence of impairments in life quality of the patients was role- physical （21.2）, bodily pain （ 39.9 ）, role-emotional （41.2）, general health （ 50.0 ）, physical functioning （ 55. 1 ）, vitality （ 60. 0 ）, mental health （ 68. 5 ）, and social functioning （70. 9）. Pearson correlation coefficients were statistically significant between bodily pain and other dimensions of life quality （ P 〈 0. 05 ）. Western medication （45.3%） was the most common treatment adopted by physicians. Conclusion： The prevalence of neuropathic pain is common in elderly patients. The three major types of neuropathic pain seriously affect the quality of life in patients. Although western medicine is the first choice of treatment, clinical drug selection should be standardized with efforts of both doctors and patients.

关 键 词：神经系统 病理学 生活质量 疼痛 焦虑 精神病状态评定量表 健康调查 

分 类 号：R741.04[医药卫生—神经病学与精神病学]