幽门螺杆菌相关microRNA在胃癌中的作用  

Role of Helicobacter pylori-related microRNA in Gastric Cancer

作　　者：师瑞[1] 王钧[1] 

机构地区：[1]解放军第451医院消化内科,710054

出　　处：《胃肠病学》2014年第3期185-187,共3页Chinese Journal of Gastroenterology

基　　金：兰州军区卫生科研基金(CXA13JA14)资助

摘　　要：已有研究提示微小RNA(miRNA)参与了多种肿瘤包括胃癌的发生、发展,幽门螺杆菌(Hp)与胃癌发生、发展关系密切。近期研究表明Hp可能通过miRNA途径促进胃癌的发生、发展。本文就胃癌相关miRNA,尤其是Hp感染相关miRNA分子及其作用机制作一综述。microRNA is thought to play an important role in the pathogenesis and development of many tumors including gastric cancer. Helicobacter pylori （Hp） is a key factor in the pathogenesis of gastric cancer. Recent data have shown that Hp may lead to gastric cancer through microRNA pathway. This article reviewed the role of gastric cancer- related miRNA especially the Hp-related miRNA in genesis of gastric cancer.

关 键 词：幽门螺杆菌 胃肿瘤 微RNAS 

分 类 号：R735.2[医药卫生—肿瘤]