^(99m)Tc-MDP全身骨显像在骨转移瘤诊断中的临床应用价值  

The Clinical Value of ^(99m)Tc-MDP Bone Scintigraphy in the Diagnosis of Bone Metastases

作　　者：张婷[1] 姚昊[1] 王志忠[1] 何宝明[1] 

机构地区：[1]中国人民解放军第309医院核医学科,北京100091

出　　处：《中国医药导刊》2013年第12期1976-1977,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨在骨转移瘤临床诊断中99mTc-MDP全身骨显像的诊断价值。方法:选取2011年1月至2012年12月间于我院临床诊断为恶性肿瘤患者330例,所有患者均进行CT及99mTc-MDP全身骨显像检查确认是否存在骨转移瘤,并将两种检查结果采用统计学软件进行对比分析。结果:330例恶性肿瘤患者中确诊恶性肿瘤骨转移者277例,CT检查诊断280例,误诊率为11.55%,漏诊率为10.11%,准确率为81.82%,敏感性为89.89%,特异性为88.45%,阳性预测值为86.28%,阴性预测值为22.64%,99mTc-MDP检查诊断242例,误诊率为4.69%,漏诊率为5.78%,准确率为91.21%,敏感性为94.22%,特异性为95.31%,阳性预测值为87.36%,阴性预测值为39.62%,两组患者敏感性、特异性及准确率间差异均比较明显,在统计学上有意义(P<0.05)。结论:99mTc-MDP全身骨显像是早期诊断骨转移瘤的安全、有效检查方法,对于恶性肿瘤患者的分期、治疗、预后具有重要意义,值得推广。Objective：To investigate the diagnostic value in the clinical diagnosis of bone metastases, 99mTc-MDP bone scintigraphy. Methods： Selected 330 cases of patients with malignant tumors in our hospital from January 2011 to December 2012, all patients underwent CT and 99mTc-MDP whole body bone scintigraphy to confirm the presence of bone metastases, and two test results were analyzed using statistical software. Results：330 patients with malignant tumors diagnosed with bone metastases of malignant tumors in 277 cases, CT examination diagnosis of 280 cases, the misdiagnosis rate was 11.55%, missed diagnosis rate was 10.11%, the accuracy rate of 81.82%, a sensitivity of 89.89%and a specificity of 88.45%, positive predictive value of 86.28%, negative predictive value of 22.64%, 99mTc-MDP check diagnosis of 242 cases, the misdiagnosis rate was 4.69%, the misdiagnosis rate was 5.78%, the accuracy was 91.21%, the sensitivity was 94.22%, specificity resistance of 95.31%, a positive predictive value of 87.36%, negative predictive value of 39.62%, the sensitivity of the two groups of patients, the difference between the specificity and accuracy are more obvious, statistically significant （P〈0.05）. Conclusion：99mTc-MDP whole body bone imaging in the early diagnosis of bone metastases safe, effective method of examination for the staging of patients with malignant tumors, the treatment, the prognosis is of great significance worthy of promotion.

关 键 词：99mTc-MDP全身骨显像 骨转移瘤 诊断 

分 类 号：R738.1[医药卫生—肿瘤]