孕期营养补充剂抗疲劳、耐寒、耐热动物实验观察  

Effect of pregnancy nutrition supplement on resistance of fatigue,cold and high temperature in mice

作　　者：暴国[1] 王宁[1] 张树成[1] 王尚明[1] 王丽丽[1] 张斌[1] 张长勇[1] 石翠格[1] 徐祥波[1] 贺斌[1] 刘庆[1] 王介东[1] 

机构地区：[1]国家人口计生委科学技术研究所,北京10081

出　　处：《中国计划生育学杂志》2014年第4期235-238,共4页Chinese Journal of Family Planning

基　　金：国家科技基础性工作专项(2013FY110100);十二五国家科技支撑计划(2012BAI32B02);国家人口计生委科学技术研究所横向课题(2013HX001)

摘　　要：目的:通过抗疲劳、耐寒、耐热实验分析孕期营养补充剂对小鼠机体生命活力的影响。方法:SPF级昆明小鼠随机分为高、中、低剂量和对照共4组,灌胃给药21d后,进行动物实验。结果:负重游泳时间在雌性小鼠的3个剂量组均明显增加(P均<0.05),在雄性小鼠的中、高剂量组明显增加(P<0.05);耐寒时间在雌性小鼠的中、高剂量组明显增加(P<0.01),在雄性小鼠的3个剂量组均明显增加(P<均0.05);耐热时间在雌性和雄性小鼠的中、高剂量组均明显增加(P<0.05)。结论:服用多种维生素、多种矿物质的营养补充剂的小鼠机体活力明显增加,抗疲劳、抗寒和抗热的能力显著提高。Objective：To explore the effect of pregnancy nutrition supplement on the resistance of fatigue,cold and high temperature in mice.Methods：SPF Kunming mice were randomly divided into 4 groups.Twenty-one days after oral administration,the resistance of fatigue,cold and high temperature were evaluated.Results：The swimming time of female mice were significantly increased in 3 does groups （P all ＜0.05）,and that was significantly increased in the medium-and high-does groups of male mice （P＜0.05）.The survival time of low temperature of female mice were significantly increased in medium-and high-does groups （P ＜0.01）,and that was significantly increased in all 3 does groups of male mice （P all ＜0.05）.The survival time of high temperature of both male and female mice were significantly increased in the medium-and high-does groups （P＜0.05）.Conclusion：Pregnancy nutrition supplement could improve the resistance of fatigue,cold and high temperature in mice.

关 键 词：多种维生素剂 维生素 矿物质 抗疲劳 耐寒 耐热 

分 类 号：R151.2[医药卫生—营养与食品卫生学]