急性脑梗死中医证候与血清vWF、PAO相关性的研究  

Study on Correlation of Acute Cerebral Infarction TCM Syndrome and Serum vWF and PAO

作　　者：方学杰[1] 李定祥[1] 易亚乔[1] 刘文华[1] 文果[1] 邓奕辉[1] 

机构地区：[1]湖南中医药大学中西医结合心脑疾病防治湖南省重点实验室,细胞生物学与分子技术湖南省高校重点实验室,湖南长沙410208

出　　处：《中华中医药学刊》2014年第4期820-822,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：湖南省教育厅项目(12A105);湖南省重点学科中西医结合基础项目;湖南省自然科学创新群体基金;湖南省高校科技创新团队;湖南省自然科学基金项目(13JJ6061);湖南省中医药科研基金项目(201319)

摘　　要：目的:探讨急性脑梗死中医证候与相关生物学指标的关系,从微观辨证的角度阐明证候与疾病的关系。方法:用ELISA法测定90例急性脑梗死急性期患者和15例正常健康者血清vWF、PAO表达水平的变化。结果:病例组血清vWF、PAO含量较健康对照组均有不同程度升高。结论:vWF、PAO血清含量变化有助于对中风病病情程度和类别的评估或判断,可作为中风病辨证分型的客观化指标。Objective：To investigate the relationship between acute cerebral infarction TCM syndrome and related bio- logical index. To elucidate the relationship between syndromes and diseases from microcosmic angle. Methods ： The levels of serum vWF and PAO were measured by ELISA in 90 cases of acute cerebral infarction with in a acute stage and 15 healthy control subjects. Results ：The levels of vWF and PAO in serum in stroke group were significant higher than that in control group （ P 〈 0. 01 ）. Conclusion ： The levels of vWF and PAO in serum contribute to the assessment of stroke and can be used as the objective indexes for the syndrome differentiation typing.

关 键 词：急性脑梗死 VWF PAO 

分 类 号：R743.33[医药卫生—神经病学与精神病学]