Intact乳腺活检系统经皮整块切除非扪及性乳腺病灶的初步研究  

A pilot study on breast lesion excision system in the single-pass en bloc excision of non-palpable breast lesions

作　　者：贺青卿[1] 朱见[1] 庄大勇[1] 郑鲁明[1] 范子义[1] 李燕宁[1] 周鹏[1] 候蕾[1] 于芳[1] 

机构地区：[1]济南军区总医院乳腺外科,济南250031

出　　处：《国际外科学杂志》2014年第3期172-174,F0003,共4页International Journal of Surgery

基　　金：山东省自然科学基金资助（No.ZR2012HM072）;济南军区总医院院长基金资助（No.2011M03）

摘　　要：目的 研究Intact乳腺活检系统对非扪及性乳腺病灶整块切除活检的有效性和安全性.方法 经医院伦理委员会批准及患者知情同意后,36例非扪及的性质不确定的乳腺病灶患者,用Intact乳腺活检系统行乳腺病灶完整切除活检,并行病理学检查,并观察其切缘.观察患者术中和术后的疼痛评分以及并发症发生情况.结果 36例患者共62个病灶均完整切除,病灶平均大小9.8 mm（2～ 13 mm）.其中46个病灶诊断为乳腺纤维腺瘤,2个病灶为乳腺导管内乳头状瘤,12个病灶为乳腺纤维腺病,1个病灶为良性分叶状肿瘤,1个病灶为浸润性导管癌.所有患者术中、术后疼痛均耐受.1例患者发生术后血肿,保守治疗后治愈,无皮肤灼伤等并发症.结论 Intact乳腺活检系统对于性质不确定的乳腺小病灶是一种安全有效的新的活检方法,并可获得完整的病灶切缘.Objective The aim of this study was to evaluate the accuracy and safety of breast lesion excision system （BLES）. Methods Following review board ethical permission and the consent of each patient, we aimed to perform a complete excision biopsy, with a margin, of small non-palpable breast lesions that the diameter less than 1.5 era. 36 patients with 62 small non-palpable breast lesions underwent a BLES biopsy. All lesions had pathobiology diagnosis. Intraoperative and postoperative pain score and complications were observed. ResultsSixty-two lesions of 36 patients had a complete excision biopsy. Mean lesion size was 9.8 mm （2-13 ram）. Forty- six lesions were diagnosed as breast fibroadenoma, two lesions as intraductal papilloma, twelve lesions as fibroade- nosis, one lesion as benign lobulated tumor, one lesion as invasive ductal carcinoma. All patients could tolerate the pain of the operation, one case occurred postoperative hematoma, cured after conservative treatment, no complica- tions such as skin burns. Conclusions The BLES biopsy is an efficacious technique at excising non-palpable breast lesions with a complete margin.

关 键 词：Intact乳腺活检系统 非扪及性乳腺病变 活检 新技术 乳腺疾病 手术后并发症 

分 类 号：R737.9[医药卫生—肿瘤]