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出 处:《中国医学创新》2014年第10期48-50,共3页Medical Innovation of China
摘 要:目的:考察丝裂霉素和羊膜移植对翼状胬肉切除术后复发率的影响。方法:对本院收治的170例患者按照随机数字表法分为三组进行手术。A组进行单纯切除术,B组联合丝裂霉素翼状胬肉切除术,C组胬肉切除联合羊膜移植术。观察手术后2周、1月、6月、1年、2年的并发症和复发情况,并进行比较。结果:在2年的术后观察期内,没有出现感染、羊膜移植排斥反应、创面溶解、复视等并发症,所有患者创面愈合良好。B、C组复发率明显低于A组,组间比较差异均有统计学意义(P<0.05)。B、C组复发率比较差异无统计学意义(P>0.05)。结论:临床上可采用联合丝裂霉素翼状胬肉切除术或胬肉切除联合羊膜移植术预防翼状胬肉切除术后复发,且两者具有价格便宜,方法容易操作,值得临床上推广使用。Objective: To investigate the influence of mitomycin and amniotic membrane transplantation ( AMT ) on recurrence rate after pterygium resection. Method: One hundred and seventy patients in the hospital were randomly divided into three groups. The group A with treated by pterygium excision, the group B with treated by combination of Mitomycin and pterygium excision, and the group C treated by the combination of amniotic membrane transplantation and pterygium excision. The recurrence rate at 2 weeks, 1 month, 6 months, 1 year, 2 years after the operation were observed and compared. Result: There was no infection, no amniotic membrane transplantation rejection and diplopia in two years, all patients worked well. The recurrence rate in group A was respectively higher than in group B and group C with significant statistical difference ( P〈0.05 ), but between Group B and C with no significantly statistical difference ( P〉0.05 ). Conclusion: Pterygium excision with mitomycin or amniotic membrane transplantation which is cheap and operates easily can be used in treating pterygium.
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