抗阻训练对老龄大鼠腓肠肌Ca^(2+)及线粒体膜电位的影响  

Effects of Resistance Training on Gastrocnemius of Ca^(2+) and Mitochondrial Membrane Potential of Aging Rats

作　　者：王震[1] 林文弢[2] 翁锡全[2] 孟艳[2] 蔺海旗[3] 

机构地区：[1]广东青年职业学院,广东广州510507 [2]广州体育学院,广东广州510500 [3]华南理工大学体育学院,广东广州510641

出　　处：《广州体育学院学报》2014年第2期85-88,共4页Journal of Guangzhou Sport University

基　　金：广东省教育厅育苗工程(LYM10096)

摘　　要：目的:通过实验研究探讨抗阻训练对老龄大鼠腓肠肌Ca2+及线粒体膜电位的影响。方法:研究对象为雄性SD大鼠,人工喂养18月龄进行8周抗阻训练干预,分别以无负重、30%、50%、70%最大负重进行训练,跑台放置坡度为35°,跑速15m/min,隔天抗阻训练。8周末检测腓肠肌胞浆Ca2+及线粒体膜电位,并与安静组比较。结果:30%、50%最大负重抗阻训练两组老龄大鼠腓肠肌Ca2+下降具有显著性意义(P<0.05);无负重、30%、50%最大负重抗阻训练三组老龄大鼠线粒体膜电位下降有极显著性差异(P<0.01)。结论:低、中等负重抗阻训练能降低衰老过程中腓肠肌胞浆Ca2+、提高线粒体膜电位,改善线粒体功能,从而预防、延迟衰老过程中线粒体功能障碍的发生。Objective： To study the effects of resistance training on the aging rats＇ gastrocnemius of Ca2＋ and mitochondrial membrane potential（mt）. Method： The male SD rats as the research object, after feeding 18 months, they were assigned as 0% , 30% , 50% , 70% maximum weight resistance training intervention. Ca2~ and mitochondrial membrane potential of gastrocnemius the aging process in the occurrence of mitochondrial dysfunctionwere tested after a period of quote of the day for 8 weeks treadmill training with the speed of 15m/min, slope as 35 o. Results： Compared with the aging control group, the gastrocnemius levels of Ca2＋ decreased and A^mt increased in the resistance training groups, among them with 30% , 50% maximum weight resistance training groups Ca2＋ decreased significantly （ P 〈 0.05, ）, and their mt increased extremely significance in 0%, 30%, 50% maximum weight resistance training groups （P 〈 0.01 ）. Conclusion： Low and moderate weight resistance training may be reduce Ca2＋ in gastrocnemius cytosolie,increased mitochondrial membrane potential, improve mitochondrial function, thereby, preventing and delaying the occurrence of mitochondrial dysfunction in the aging process.

关 键 词：抗阻训练 衰老 腓肠肌 CA2+ 线粒体膜电位 

分 类 号：G804.23[文化科学—运动人体科学]