傅里叶光学相干断层扫描测量上海市宝山区儿童房角相关参数  

Distribution of anterior chamber angle parameters measured by Fourier-domain optical coherence tomography in children in Baoshan District of Shanghai,China

作　　者：李美丽[1] 邹海东[1,2] 庞昆[3] 何鲜桂[2] 陆丽娜[2] 朱剑锋[2] 

机构地区：[1]上海交通大学附属第一人民医院眼科,上海市200080 [2]上海市眼病防治中心,上海市200040 [3]徐州市中心医院泌尿外科,江苏省徐州市221009

出　　处：《眼科新进展》2014年第4期341-344,共4页Recent Advances in Ophthalmology

基　　金：上海市加强公共卫生体系建设三年行动计划(2011-2013)项目(编号:2011-15);上海市卫生局重点课题(编号:20114007);上海市卫生局青年科研项目(编号:2010Y113);上海市公共卫生优秀青年人才培养计划(编号:08GWQ036)~~

摘　　要：目的利用RTVue傅里叶光学相干断层扫描（FD—OCT）对正常学龄儿童的前房角各参数进行测量研究。方法在上海市宝山区小学中纳入272名儿童作为研究对象，采用FD-OCT对房角开放距离500μm、7501μm及小梁网一虹膜空间面积、房角隐窝面积、房角角度4个反映房角开放程度的参数进行测量，研究房角各参数与年龄、性别及眼轴长度的关系。结果男女性剐问各房角参数测量值的差异均无统计学意义（均为P〉0．05）；房角开放距离、小梁网一虹膜空间面积、房角隐窝面积及房角角度均与年龄及眼轴长度呈正相关（相关系数r分别为0．61～0．73、0．51—0．61，均为P〈0．0001）；各个年龄段之间（7．9岁与10～12岁、7—9岁与13～15岁、10～12岁与13～15岁）的参数值差异均有统计学意义（均为P〈0．0001）。结论性别不是影响儿童房角结构变化的主要因素；各房角参数随着年龄增长而增加，并与眼轴长度呈显著正相关。Objective To study the anterior chamber angle parameters of the normal school-age children using the RTVue Fourier-domain optical coherence tomo- graphy （FD-OCT）. Methods A total of 272 children in primary school in Baoshml District of Shanghai, China were enrolled, the relationship between angle parameters measured by FC-OCT and age, sex, and axial length were explored, the parameters in- cluding angle opening distance at 500 μm and 750 μm, trabecular-iris space area at 500 μm and 750 μm, angle recessus area at 500μm and 750 μm, anterior chamber angle at 500 μm and 750 μm. Results The angle parameter values between boys and girls were not statistically significant （ all P 〉 0.05 ） ; The angle opening distance, angle re- cessus area, trabecular-iris space area and anterior chamber angle at 500μm and 750 μm were positively correlated with age and axial length （ correlation coefficient r were from 0.51 to 0.73, from 0.51 to 0.50 separately, all P 〈0.000 1 ） ; The parameter value between different ages （7 -9 years and l0 -12 years, 7 -9 years and 13 -15 years, 10 - 12 years and 13 - 15 years） were statistically significant （ all P 〈 0. 000 1 ）. Conclu- sion Gender is not the main factor on the changes of children angle structure; The angle parameters increase with age prolong and are positively correlated with axial length.

关 键 词：前房角 RTVue傅里叶光学相干断层扫描 儿童 眼轴长度 

分 类 号：R774.5[医药卫生—眼科]