简易调强计划设计方法在上段食管癌中的应用  

Upper esophageal carcinoma plan design used Simple intensity modulated radiotherapy treatment method

作　　者：袁军[1] 郭海亮[1] 谢美荣[1] 付爽[1] 王祥财[1] 许明君[1] 

机构地区：[1]赣南医学院第一附属医院放疗科,江西赣州341000

出　　处：《赣南医学院学报》2014年第1期31-33,50,共4页JOURNAL OF GANNAN MEDICAL UNIVERSITY

基　　金：2011年赣州市科技局课题

摘　　要：目的:介绍一种简易调强计划设计方法在上段食管癌中的应用。方法:选取6例胸上段食管癌患者,分别制定传统9野调强计划和简易调强计划,统一处方剂量60 Gy/30 F,比较靶区、危及器官的剂量体积参数,加速器的总机器跳数(MU)。结果:传统9野调强计划与简易调强计划的靶区剂量分布基本一致。对于高剂量区1%体积的脊髓受量和双肺20 Gy和30 Gy照射的肺体积百分比(V20,V30),两种计划的结果无明显差异(P>0.05)。但简易调强设计方法可以减少脊髓、肺两种重要器官的低剂量受照体积,同时减少投射跳数(P<0.05)。结论:简易调强设计方法可以在胸上段食管癌中应用。Objective：Introduced a simple intensity modulated radiotherapy treatment plan（slMRT） method used in upper esophageal carcinoma. Methods ： Six patients with upper thoracic esophageal cancer were included, IMRT with nine field （IMRT） and simple intensity modulated radiotherapy treatment plan were generated, Dose prescription was set to 60 Gy in 30 fractions, Dose volume histograms and MU were evaluated to assess plan quality. Results ： The PTV coverage compare to IMRT and sIMRT were basically the same, There was no difference in the max dose of spinal cord and V20 ,V30 of lung （P 〉 0.05 ）. But slMRT could reduce Low dose irradiated volume of spinal,lung and reduce the MU/fraction （P 〈 0.05 ）. Conclusions ： The simple intensity modulated plan design method can used in upper esophageal carcinoma.

关 键 词：上段食管癌 简易调强放疗 角度优化 

分 类 号：R730.55[医药卫生—肿瘤]