大连市老年出血性脑卒中患者的危险因素分析  

The risk factors analysis of patients with hemorrhagic stroke in Zhongshan district of Dalian city

作　　者：赵洁[1] 

机构地区：[1]大连大学附属中山医院神经内科,116001

出　　处：《中国综合临床》2014年第4期389-391,共3页Clinical Medicine of China

摘　　要：目的 探讨大连市老年出血性脑卒中患者的相关危险因素,旨在制定个体化、有针对性的防护和干预措施.方法 选取2011年10月至2013年8月期间我院收治的＞60岁的老年出血性脑卒中患者183例,以及同期健康体检者158名,分别列为观察组和对照组.对两组人群的临床资料、生活习惯等进行调查,并测量其身高、体质量,计算体质量指数（BMI）;检测两组患者血脂和血浆纤维蛋白原浓度.结果 男性[126例（68.85％）]70岁以上[119例（65.03％）]、且BMI≥25 kg/m2[113例（61.75％）]、伴有原发性高血压史（141例（77.05％）、吸烟[59例（32.24％）]等不良习惯、甘油三酯（TG）≥1.7 mmol/L[94例（51.37％）]、总胆固醇（TC）≥5.7 mmol/L[[114例（62.30％）]、纤维蛋白原＜4.0 g/L[125例（68.31％）],符合该类条件的患者以观察组为多,且明显多于对照组人群[82例（51.90％）、71例（44.94％）、63例（39.87％）、28例（17.72％）、30例（18.99％）、46例（29.11％）、57例（36.08％）、131例（82.91％）],两组比较差异均有统计学意义（x2值分别为8.725、27.167、12.742、95.064、5.825、14.056、18.478、7.314,P均＜0.05）;而糖尿病史、习惯性饮酒、高密度脂蛋白胆固醇（HDL-C）及低密度脂蛋白胆固醇（LDL-C）水平两组患者没有表现出明显的差异性（P均＞0.05）.结论 老年出血性脑卒中的发病与多种因素密切相关,男性、年龄＞ 70岁、吸烟、高血压史、肥胖、高血脂（TG≥1.7 mmol/L、TC≥5.7mmol/L）是老年出血性脑卒中的重要独立危险因素.临床上对患者的血压和血脂进行控制,合理指导患者的膳食,使患者保持良好的心态,适当锻炼,劝其改变吸烟、喝酒等不良生活习惯,对预防老年出血性脑卒中的发生具有重要意义.Objective To explore the risk factors analysis of patients with hemorrhagic stroke in Zhongshan district of Dalian city in order to providing the Corresponding intervention measures.Methods From Oct 2010 to Aug 2013,183 cases of patients with hemorrhagic stroke（age 〉 60 years old） and 158 cases healthy physical people in Zhongshan Hospital Affiliated to Dalian University were served as observation group and control group.Clinical information and life habit of two groups were recorded,the height and weight were measured,body mess index （BMI） was calculated,blood lipid level and plasma fiber protein level were detected.Results The rate of male,age 〉70 years,BMI index ≥25 kg/m2,smoking,history of hypertension,TG ≥ 1.7 mmol/L,TC ≥ 5.7 mmol/L,fibrinogen 〈 4.0 g/L in observation group were 68.85 % （126/183）,65.03% （119/183）,61.75% （113/183）,77.05% （141/183）,32.24% （59/183）,51.37% （94/183）,62.30% （114/183）,68.31% （125/183） respectively,higher than those of control group （51.90% （82/158）,44.94% （71/158）,39.87% （63/158）,17.72% （28/158）,18.99% （30/158）,29.11% （46/158）,36.08% （57/158）,82.91% （131/158）,the differences were statistically significant （x2 =8.725,27.167,12.742,95.064,5.825,14.056,18.478,7.314,P 〈 0.05）.However,there were no significant differences in terms of diabetes history,drinking,high density lipoprotein-cholesterol level and low density lipoprotein-cholesterol between two groups.Conclusion Hemorrhagic stroke is closely related to many factors.Sex,age 〉 70 years,smoking,obesity,history of hypertension,high cholesterin （TC ≥ 5.7 mmol/L） are independent risk factors of patients with hemorrhagic stroke in elderly.Through the control target population＇s blood pressure and blood lipids,rational diet,appropriate exercise,quit smoking and alcohol,adjust the good point of view,we can prevent the occurrence old hemorrhagic stroke.

关 键 词：老年人 出血性脑卒中 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]