解酒天然药物研究进展  

The progress in developing natural drugs for prevention and cure of alcoholic intoxication

作　　者：张若明[1] 李经才[1] 

机构地区：[1]沈阳药科大学药学系,辽宁沈阳110016

出　　处：《沈阳药科大学学报》2001年第2期138-142,共5页Journal of Shenyang Pharmaceutical University

摘　　要：过量饮酒可引起人体生理功能紊乱乃至死亡 ,开发有效的解酒药物具有重要的意义和广阔的市场前景。当前天然解酒药物的作用机制是通过抑制乙醇胃肠吸收和加速代谢以降低机体血醇浓度 ,解除醉酒状态。文章论述了人参、葛花、枳木具子等多种天然解酒药物的单方和复方解酒作用药理研究的最新进展 ,探讨其活性成分的构效关系 ;It has been found that excessive ingestion of ethanol usually brings about physical dyfunction,even death. The article reviewed the characterization of ethanol metabolism,the kinds of drugs for prevention and cure of alcoholic intoxication,the mechanism for lowering blood alcoholic level,the structure activity relationships from some natural drugs,and the effects of complex prescriptions of traditional Chinese medicines.

关 键 词：天然药物 酒精中毒 乙醇脱氢酶 胃肠吸收 

分 类 号：R259.956[医药卫生—中西医结合]