复发和初发性脑梗死患者血清同型半胱氨酸、血浆D-二聚体及全血组织因子促凝活性的测定  

The determination of the early onset and recurrent of cerebral infarction patients,serum homocysteine plasma D-dimer and whole blood coagulant activity organization factors

作　　者：张明洁[1] 刘水晶[1] 朱杰平[1] 毛洪博 李明[1] 

机构地区：[1]武汉科技大学附属天佑医院检验科,武汉430064

出　　处：《临床血液学杂志》2014年第2期115-116,共2页Journal of Clinical Hematology

摘　　要：目的:分析复发和初发性脑梗死患者血清同型半胱氨酸(Hcy)、血浆D-二聚体(DD)及全血组织因子促凝活性(TF-PCA)的变化。方法:使用仪器法对70例复发性脑梗死(复发组)及80例初发性脑梗死(初发组)患者的血清Hcy、血浆DD及全血TF-PCA水平进行检测,并与80例健康体检者(对照组)进行对比分析。结果:与对照组比较,复发组和初发组Hcy、DD及TF-PCA含量均增高,复发组升高更显著。结论:脑梗死患者Hcy、DD、TF-PCA血液水平检测,对复发和初发性脑梗死的诊断及疗效观察有重要临床意义。Objective：Analysis on the changes of the early onset and recurrent of cerebral infarction patients se- rum homocysteine （Hcy） plasma D-dimer （DD） and whole blood coagulant activity organization factors （TF- PCA）. Method：After testing on 70 early onset and 80 recurrent of cerebral infarction patients serum Hcy,plasma DD and whole blood TF-FCA,and make a comparison with 80 healthy controls（control group）. Result： Compared with the control group, the early onset and recurrent of cerebral infarction patients＇ Hcy, DD and TF-PCA in- creased,but recurrent of cerebral infarction patients had a obvious increasing （P〈0.05 or P〈0.01）. Conclusion： Acute cerebral infarction patients Hcy,DD and TF-PCA blood oxygen level dependent has clinical significance in the determination and clinical observation of the early onset and recurrent of cerebral infarction patients.

关 键 词：复发性脑梗死 初发性脑梗死 同型半胱氨酸 D-二聚体 组织因子促凝活性 

分 类 号：R743.33[医药卫生—神经病学与精神病学]